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5U31
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BU of 5u31 by Molmil
Crystal structure of AacC2c1-sgRNA-8mer substrate DNA ternary complex
分子名称: CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ...
著者Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J.
登録日2016-12-01
公開日2017-01-25
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
2JMJ
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BU of 2jmj by Molmil
NMR solution structure of the PHD domain from the yeast YNG1 protein in complex with H3(1-9)K4me3 peptide
分子名称: Histone H3, Protein YNG1, ZINC ION
著者Ilin, S, Taverna, S.D, Rogers, R.S, Tanny, J.C, Lavender, H, Li, H, Baker, L, Boyle, J, Blair, L.P, Chait, B.T, Patel, D.J, Aitchison, J.D, Tackett, A.J, Allis, C.D.
登録日2006-11-15
公開日2007-07-03
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
Mol.Cell, 24, 2006
2KGG
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BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
分子名称: Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-11
公開日2009-05-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2H6N
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BU of 2h6n by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me2 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H6Q
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BU of 2h6q by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-06-01
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2GKU
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BU of 2gku by Molmil
Monomeric human telomere DNA tetraplex with 3+1 strand fold topology, two edgewise loops and double-chain reversal loop, NMR, 12 structures
分子名称: Human telomere DNA
著者Luu, K.N, Phan, A.T, Kuryavyi, V.V, Lacroix, L, Patel, D.J.
登録日2006-04-03
公開日2006-08-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold.
J.Am.Chem.Soc., 128, 2006
2H68
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BU of 2h68 by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H6K
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BU of 2h6k by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2KF7
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BU of 2kf7 by Molmil
Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution (with G7-to-BRG substitution)
分子名称: HUMAN TELOMERE DNA
著者Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T.
登録日2009-02-12
公開日2009-03-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
2KGI
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BU of 2kgi by Molmil
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
分子名称: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-12
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KF8
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BU of 2kf8 by Molmil
Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution
分子名称: HUMAN TELOMERE DNA
著者Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T.
登録日2009-02-12
公開日2009-03-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
2KYO
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BU of 2kyo by Molmil
Dimeric human ckit-2 proto-oncogene promoter quadruplex DNA NMR, 10 structures
分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Phan, A.T, Patel, D.J.
登録日2010-06-05
公開日2010-06-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
5VW1
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BU of 5vw1 by Molmil
Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, DI(HYDROXYETHYL)ETHER, ...
著者Yang, H, Patel, D.J.
登録日2017-05-21
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9.
Mol. Cell, 67, 2017
2KPR
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BU of 2kpr by Molmil
Monomeric intronic human chl1 gene quadruplex DNA NMR, 17 structures
分子名称: 5'-D(*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Patel, D.J.
登録日2009-10-19
公開日2010-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence.
Structure, 18, 2010
2KYP
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BU of 2kyp by Molmil
Monomeric Human CKIT-2 proto-oncogene promoter quadruplex DNA NMR, 12 structures
分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Phan, A.T, Patel, D.J.
登録日2010-06-06
公開日2010-06-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
2JSM
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BU of 2jsm by Molmil
MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural
分子名称: HUMAN TELOMERE DNA
著者Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
登録日2007-07-09
公開日2008-07-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution
Nucleic Acids Res., 35, 2007
2JMI
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BU of 2jmi by Molmil
NMR solution structure of PHD finger fragment of Yeast Yng1 protein in free state
分子名称: Protein YNG1, ZINC ION
著者Ilin, S, Taverna, S.D, Rogers, R.S, Tanny, J.C, Lavender, H, Li, H, Baker, L, Boyle, J, Blair, L.P, Chait, B.T, Patel, D.J, Aitchison, J.D, Tackett, A.J, Allis, C.D.
登録日2006-11-15
公開日2007-07-03
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
Mol.Cell, 24, 2006
2JSL
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BU of 2jsl by Molmil
Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 Natural, NMR, 10 Structures
分子名称: HUMAN TELOMERE DNA
著者Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
登録日2007-07-08
公開日2008-07-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
3F73
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Alignment of guide-target seed duplex within an argonaute silencing complex
分子名称: ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), MAGNESIUM ION, ...
著者Wang, Y, Li, H, Sheng, G, Juranek, S, Tuschl, T, Patel, D.J.
登録日2008-11-07
公開日2008-12-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.
Nature, 456, 2008
3DLB
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BU of 3dlb by Molmil
Crystal structure of the guide-strand-containing Argonaute protein silencing complex
分子名称: DNA (5'-D(*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DA)-3'), argonaute
著者Wang, Y, Sheng, G, Patel, D.J.
登録日2008-06-26
公開日2008-09-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the guide-strand-containing argonaute silencing complex.
Nature, 456, 2008
3D1B
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Tetragonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3DLH
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BU of 3dlh by Molmil
Crystal structure of the guide-strand-containing Argonaute protein silencing complex
分子名称: ACETIC ACID, Argonaute, DNA (5'-D(DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DAP*DTP*DAP*DGP*DT)-3'), ...
著者Wang, Y, Sheng, G, Patel, D.J.
登録日2008-06-27
公開日2008-09-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the guide-strand-containing argonaute silencing complex.
Nature, 456, 2008
3GIK
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Dpo4 extension ternary complex with the oxoG(anti)-C(anti) pair
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', ...
著者Rechkoblit, O, Malinina, L, Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIJ
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Dpo4 extension ternary complex with oxoG(syn)-A(anti) and oxoG(anti)-A(syn) pairs
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', ...
著者Rechkoblit, O, Malinina, L, Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIM
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Dpo4 extension ternary complex with oxoG(anti)-G(syn) pair
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DDG))-3', ...
著者Rechkoblit, O, Malinina, L, Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009

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