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5U31

Crystal structure of AacC2c1-sgRNA-8mer substrate DNA ternary complex

Summary for 5U31
Entry DOI10.2210/pdb5u31/pdb
Related5U30 5U33 5U34
DescriptorCRISPR-associated endonuclease C2c1, sgRNA, Target DNA strand, ... (5 entities in total)
Functional Keywordstype v crispr-cas endonculease: c2c1: structure: binary complex with sgrna: ternary complex with added dna: ruvc catalytic pocket: sequence-specific pam recognition: genome editing tool, hydrolase-dna complex, hydrolase/dna
Biological sourceAlicyclobacillus acidoterrestris
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Total number of polymer chains5
Total formula weight181552.43
Authors
Yang, H.,Gao, P.,Rajashankar, K.R.,Patel, D.J. (deposition date: 2016-12-01, release date: 2017-01-25, Last modification date: 2020-01-01)
Primary citationYang, H.,Gao, P.,Rajashankar, K.R.,Patel, D.J.
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167:1814-1828.e12, 2016
Cited by
PubMed: 27984729
DOI: 10.1016/j.cell.2016.11.053
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

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