3F73
Alignment of guide-target seed duplex within an argonaute silencing complex
Summary for 3F73
Entry DOI | 10.2210/pdb3f73/pdb |
Related | 3DLB 3DLH |
Descriptor | ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*AP*A*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3'), ... (6 entities in total) |
Functional Keywords | argonaute, protein-dna-rna-complex, nucleic acid binding protein-dna-rna complex, nucleic acid binding protein/dna/rna |
Biological source | Thermus thermophilus |
Total number of polymer chains | 6 |
Total formula weight | 179299.39 |
Authors | Wang, Y.,Li, H.,Sheng, G.,Juranek, S.,Tuschl, T.,Patel, D.J. (deposition date: 2008-11-07, release date: 2008-12-16, Last modification date: 2023-09-06) |
Primary citation | Wang, Y.,Juranek, S.,Li, H.,Sheng, G.,Tuschl, T.,Patel, D.J. Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature, 456:921-926, 2008 Cited by PubMed: 19092929DOI: 10.1038/nature07666 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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