3F73

Alignment of guide-target seed duplex within an argonaute silencing complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ARGONAUTE	polymer	685	76728.7	2	UniProt (Q746M7) Pfam (PF22472) Pfam (PF18309) Pfam (PF22474) In PDB	Thermus thermophilus
2	C, X	DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3')	polymer	21	6588.3	2
3	H, Y	RNA (5'-R(*UP*AP*UP*AP*CP*AP*A*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3')	polymer	20	6248.8	2
4	A, C, X	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	C	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
6		water	water		18.0	16	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	179131.5
Non-Polymers*	Number of molecules	4
	Total formula weight	167.9
All*	Total formula weight	179299.4

*Water molecules are not included.