2KGG

Solution Structure of JARID1A C-terminal PHD finger

Summary for 2KGG

Entry DOI	10.2210/pdb2kgg/pdb
NMR Information	BMRB: 16209
Descriptor	Histone demethylase JARID1A, ZINC ION (2 entities in total)
Functional Keywords	phd finger, jarid1a, histone modification, leukemia, alternative splicing, chromatin regulator, developmental protein, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, metal binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	5933.31
Authors	Song, J.,Wang, Z.,Patel, D.J. (deposition date: 2009-03-11, release date: 2009-05-05, Last modification date: 2020-02-26)
Primary citation	Wang, G.G.,Song, J.,Wang, Z.,Dormann, H.L.,Casadio, F.,Li, H.,Luo, J.L.,Patel, D.J.,Allis, C.D. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459:847-851, 2009 Cited by PubMed: 19430464 DOI: 10.1038/nature08036 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation