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6UUH
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BU of 6uuh by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody 438-B11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B11 Fab Heavy Chain, B11 Fab Light Chain, ...
著者Kumar, S, Wilson, I.A.
登録日2019-10-30
公開日2020-09-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Sci Adv, 6, 2020
7Y3O
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BU of 7y3o by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody BIOLS56
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, Light chain of BIOLS56, ...
著者Rao, X, Gao, F, Wu, Y, Gao, F.
登録日2022-06-11
公開日2023-12-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
7Y3N
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BU of 7y3n by Molmil
Crystal structure of SARS-CoV receptor binding domain in complex with human antibody BIOLS56
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, ...
著者Rao, X, Chai, Y, Wu, Y, Gao, F.
登録日2022-06-11
公開日2023-12-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8QJJ
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BU of 8qjj by Molmil
CTE type II (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2023-09-13
公開日2023-10-18
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
9IK9
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BU of 9ik9 by Molmil
Cryo-EM Structure of SST analogs bond SSTR1-Gi complex
分子名称: (4J2)(DCY)(DTY)(DTR)K(DVA)(DCY)(ALO)(NH2), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wong, T.S, Zeng, Z.C, Xiong, T.T, Gan, S.Y, Du, Y.
登録日2024-06-26
公開日2025-04-30
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural insights into the binding modes of lanreotide and pasireotide with somatostatin receptor 1.
Acta Pharm Sin B, 15, 2025
9IK8
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BU of 9ik8 by Molmil
Cryo-EM Structure of SSTR1-Gi SST analogs complex
分子名称: DTR-LYS-TY5-PHA-A1D5E-004, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wong, T.S, Zeng, Z.C, Xiong, T.T, Gan, S.Y, Du, Y.
登録日2024-06-26
公開日2025-04-30
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Structural insights into the binding modes of lanreotide and pasireotide with somatostatin receptor 1.
Acta Pharm Sin B, 15, 2025
4B61
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BU of 4b61 by Molmil
In meso structure of alginate transporter, AlgE, from Pseudomoas aeruginosa, PAO1. Crystal form 3.
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ACETATE ION, ...
著者Tan, J, Pye, V.E, Aragao, D, Caffrey, M.
登録日2012-08-08
公開日2013-07-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4AZL
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BU of 4azl by Molmil
In meso structure of alginate transporter, AlgE, from Pseudomoas aeruginosa, PAO1, crystal form 2.
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALGINATE PRODUCTION PROTEIN ALGE, ...
著者Tan, J, Pye, V.E, Aragao, D, Caffrey, M.
登録日2012-06-26
公開日2013-07-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
7XST
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BU of 7xst by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike glycoprotein in complex with three F61 Fab and three D2 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
著者Wang, X, Li, X.
登録日2022-05-15
公開日2022-11-23
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XMX
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BU of 7xmx by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three F61 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F61 heavy chain, F61 light chain, ...
著者Wang, X, Li, X.
登録日2022-04-27
公開日2022-11-23
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
6V6W
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BU of 6v6w by Molmil
Crystal structure of antibody 438-B11 DSS mutant (Cys98A-100aA) in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy chain, ...
著者Kumar, S, Wilson, I.A.
登録日2019-12-06
公開日2020-09-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
Sci Adv, 6, 2020
4AFK
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BU of 4afk by Molmil
In meso structure of alginate transporter, AlgE, from Pseudomonas aeruginosa, PAO1
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ...
著者Tan, J, Pye, V.E, Aragao, D, Caffrey, M.
登録日2012-01-19
公開日2013-02-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
9JCV
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BU of 9jcv by Molmil
Cryo-EM structure of human TauT in the apo state, determined in an inward-facing open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Sodium- and chloride-dependent taurine transporter
著者Qu, Q, Chao, Y, Zhou, Z.
登録日2024-08-30
公開日2025-03-19
最終更新日2025-05-07
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Transport and inhibition mechanism for human TauT-mediated taurine uptake.
Cell Res., 35, 2025
6UTK
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BU of 6utk by Molmil
Crystal structure of 438-B11 Fab in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22 at 3.80 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kumar, S, Wilson, I.A.
登録日2019-10-29
公開日2020-09-23
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
Sci Adv, 6, 2020
9JD6
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BU of 9jd6 by Molmil
Cryo-EM structure of human TauT in presence of Piperidine-4-sulfonate, determined in an inward-facing occluded conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ...
著者Qu, Q, Chao, Y, Zhou, Z.
登録日2024-08-30
公開日2025-03-19
最終更新日2025-05-07
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Transport and inhibition mechanism for human TauT-mediated taurine uptake.
Cell Res., 35, 2025
9JD5
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BU of 9jd5 by Molmil
Cryo-EM structure of human TauT in presence of Taurocyamine, determined in an inward-facing occluded conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ...
著者Qu, Q, Chao, Y, Zhou, Z.
登録日2024-08-30
公開日2025-03-19
最終更新日2025-05-07
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Transport and inhibition mechanism for human TauT-mediated taurine uptake.
Cell Res., 35, 2025
9JCZ
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BU of 9jcz by Molmil
Cryo-EM structure of human TauT in presence of taurine, determined in an inward-facing occluded conformation
分子名称: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Qu, Q, Chao, Y, Zhou, Z.
登録日2024-08-30
公開日2025-03-19
最終更新日2025-05-07
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Transport and inhibition mechanism for human TauT-mediated taurine uptake.
Cell Res., 35, 2025
9JLN
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BU of 9jln by Molmil
Cryo-EM structure of human TauT in presence of taurine, observed only one sodium ion, determined in an inward-occluded conformation
分子名称: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Qu, Q, Chao, Y, Zhou, Z.
登録日2024-09-19
公開日2025-03-19
最終更新日2025-05-07
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Transport and inhibition mechanism for human TauT-mediated taurine uptake.
Cell Res., 35, 2025
8UFD
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BU of 8ufd by Molmil
Multidrug efflux pump MtEfpA bound with inhibitor BRD8000.3
分子名称: (1S,3S)-N-[6-bromo-5-(pyrimidin-2-yl)pyridin-2-yl]-2,2-dimethyl-3-(2-methylpropyl)cyclopropane-1-carboxamide, Integral membrane efflux protein EFPA, PHOSPHATIDYLETHANOLAMINE
著者Wang, S, Liao, M.
登録日2023-10-04
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition.
Nat Commun, 15, 2024
8UFE
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BU of 8ufe by Molmil
Multidrug efflux pump EfpA from mycobacterium smegmatis
分子名称: Integral membrane efflux protein EfpA, PHOSPHATIDYLETHANOLAMINE
著者Wang, S, Liao, M.
登録日2023-10-04
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition.
Nat Commun, 15, 2024
8IM6
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BU of 8im6 by Molmil
Crystal structure of HCoV 229E main protease in complex with PF07304814
分子名称: 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate
著者Zhou, Y.R, Zeng, P, Zhang, J, Li, J.
登録日2023-03-06
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332.
Biochem.Biophys.Res.Commun., 657, 2023
7OTJ
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BU of 7otj by Molmil
Crystal structure of Pif1 helicase from Candida albicans
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Rety, S, Xi, X.G.
登録日2021-06-10
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural study of the function of Candida Albicans Pif1.
Biochem.Biophys.Res.Commun., 567, 2021
7TEI
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BU of 7tei by Molmil
SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Stalls, V, Acharya, P.
登録日2022-01-05
公開日2022-02-16
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022
7TF8
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BU of 7tf8 by Molmil
SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Stalls, V, Acharya, P.
登録日2022-01-06
公開日2022-02-16
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022
7THT
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BU of 7tht by Molmil
CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 heavy chain, ...
著者Manne, K, May, A, Acharya, P.
登録日2022-01-12
公開日2022-02-16
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022

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