9JD6

Cryo-EM structure of human TauT in presence of Piperidine-4-sulfonate, determined in an inward-facing occluded conformation

This is a non-PDB format compatible entry.

Summary for 9JD6

• Entry DOI: 10.2210/pdb9jd6/pdb
• EMDB information: 61382
• Descriptor: Sodium- and chloride-dependent taurine transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: human taurine transporter, piperidine-4-sulfonate, complex, inward-facing occluded conformation, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 70356.72

Authors

Qu, Q.,Chao, Y.,Zhou, Z. (deposition date: 2024-08-30, release date: 2025-03-19)

• Primary citation: Chao, Y.,Zhou, Z.,Xia, H.,Yang, C.,Li, T.,Tang, Y.Q.,Shu, Y.,Ba, Q.,Hong, J.,Li, D.,Qu, Q.; Transport and inhibition mechanism for human TauT-mediated taurine uptake.; Cell Res., 2025; PubMed: 39837997; DOI: 10.1038/s41422-025-01076-w

Experimental method

ELECTRON MICROSCOPY (3.06 Å)