9JCZ

Cryo-EM structure of human TauT in presence of taurine, determined in an inward-facing occluded conformation

Summary for 9JCZ

• Entry DOI: 10.2210/pdb9jcz/pdb
• EMDB information: 61378
• Descriptor: Sodium- and chloride-dependent taurine transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... (7 entities in total)
• Functional Keywords: human taut, taurine transporter, taurine, inward- facing occluded conformation, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 71313.10

Authors

Qu, Q.,Chao, Y.,Zhou, Z. (deposition date: 2024-08-30, release date: 2025-03-19, Last modification date: 2025-05-07)

• Primary citation: Chao, Y.,Zhou, Z.,Xia, H.,Yang, C.,Li, T.,Tang, Y.Q.,Shu, Y.,Ba, Q.,Hong, J.,Li, D.,Qu, Q.; Transport and inhibition mechanism for human TauT-mediated taurine uptake.; Cell Res., 35:381-384, 2025; PubMed: 39837997; DOI: 10.1038/s41422-025-01076-w

Experimental method

ELECTRON MICROSCOPY (2.64 Å)