6YOF
| Structure of PepTSt from COC IMISX setup collected by rotation serial crystallography on crystals prelocated by 2D X-ray phase-contrast imaging | 分子名称: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 2-(2-METHOXYETHOXY)ETHANOL, Di-or tripeptide:H+ symporter, ... | 著者 | Huang, C.-Y, Martiel, I, Villanueva-Perez, P, Panepucci, E, Caffrey, M, Wang, M. | 登録日 | 2020-04-14 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Low-dose in situ prelocation of protein microcrystals by 2D X-ray phase-contrast imaging for serial crystallography. Iucrj, 7, 2020
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1BAH
| A TWO DISULFIDE DERIVATIVE OF CHARYBDOTOXIN WITH DISULFIDE 13-33 REPLACED BY TWO ALPHA-AMINOBUTYRIC ACIDS, NMR, 30 STRUCTURES | 分子名称: | CHARYBDOTOXIN | 著者 | Song, J, Gilquin, B, Jamin, N, Guenneugues, M, Dauplais, M, Vita, C, Menez, A. | 登録日 | 1996-06-06 | 公開日 | 1997-01-11 | 最終更新日 | 2020-01-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing. Biochemistry, 36, 1997
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6LNG
| Rapid crystallization of streptavidin using charged peptides | 分子名称: | GLYCEROL, Streptavidin | 著者 | Minamihata, K, Tsukamoto, K, Adachi, M, Shimizu, R, Mishina, M, Kuroki, R, Nagamune, T. | 登録日 | 2019-12-30 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8000015 Å) | 主引用文献 | Genetically fused charged peptides induce rapid crystallization of proteins. Chem.Commun.(Camb.), 56, 2020
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6OWJ
| Zn-mediated polymerization of human SFPQ | 分子名称: | Splicing factor, proline- and glutamine-rich, ZINC ION | 著者 | Lee, M. | 登録日 | 2019-05-10 | 公開日 | 2020-02-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ. Nucleic Acids Res., 48, 2020
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1AXH
| ATRACOTOXIN-HVI FROM HADRONYCHE VERSUTA (AUSTRALIAN FUNNEL-WEB SPIDER, NMR, 20 STRUCTURES | 分子名称: | ATRACOTOXIN-HVI | 著者 | Fletcher, J.I, O'Donoghue, S.I, Nilges, M, King, G.F. | 登録日 | 1996-11-04 | 公開日 | 1997-11-12 | 最終更新日 | 2021-02-03 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider. Nat.Struct.Biol., 4, 1997
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6LP1
| Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei. | 分子名称: | CALCIUM ION, GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase | 著者 | Mochizuki, K, Inaoka, D.K, Shiba, T, Fukuda, K, Kurasawa, H, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Balogun, E.O, Harada, S, Hirayama, K, Kita, K. | 登録日 | 2020-01-08 | 公開日 | 2020-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei. Biochim Biophys Acta Bioenerg, 1861, 2020
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5YEG
| Crystal structure of CTCF ZFs4-8-Hs5-1a complex | 分子名称: | DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3'), Transcriptional repressor CTCF, ... | 著者 | Yin, M, Wang, J, Wang, M, Li, X. | 登録日 | 2017-09-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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6YMG
| VcaM4I restriction endonuclease in complex with 5mC-modified dsDNA | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*A)-3'), DNA (5'-D(P*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), ... | 著者 | Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M. | 登録日 | 2020-04-08 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA. Nucleic Acids Res., 49, 2021
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8RXR
| Crystal structure of VPS34 in complex with inhibitor SB02024 | 分子名称: | 4-[(3R)-3-methylmorpholin-4-yl]-2-[(2R)-2-(trifluoromethyl)piperidin-1-yl]-3H-pyridin-6-one, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | 著者 | Tresaugues, L, Yu, Y, Bogdan, M, Parpal, S, Silvander, C, Lindstrom, J, Simeon, J, Timson, M.J, Al-Hashimi, H, Smith, B.D, Flynn, D.L, Viklund, J, Martinsson, J, De Milito, A, Andersson, M. | 登録日 | 2024-02-07 | 公開日 | 2024-03-20 | 最終更新日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy. Mol Oncol, 18, 2024
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6AHV
| Crystal structure of human RPP40 | 分子名称: | Ribonuclease P protein subunit p40 | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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7PQT
| Apo human Kv3.1 cryo-EM structure | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | 著者 | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | 登録日 | 2021-09-20 | 公開日 | 2022-08-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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7PQU
| Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563) | 分子名称: | 1-(4-methylphenyl)sulfonyl-N-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | 著者 | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | 登録日 | 2021-09-20 | 公開日 | 2022-08-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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7SQO
| Structure of the orexin-2 receptor(OX2R) bound to TAK-925, Gi and scFv16 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | McGrath, A.P, Kang, Y, Flinspach, M. | 登録日 | 2021-11-05 | 公開日 | 2022-05-25 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Molecular mechanism of the wake-promoting agent TAK-925. Nat Commun, 13, 2022
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8RZL
| Sulfolobus acidocaldarius threads (0406) filament. | 分子名称: | Sulfolobus acidocaldarius threads (0406) filament., alpha-D-mannopyranose, beta-D-glucopyranose-(1-4)-6-deoxy-6-sulfo-beta-D-glucopyranose-(1-3)-[alpha-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Isupov, M.N, Gaines, M, McLaren, M, Daum, B. | 登録日 | 2024-02-12 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Sulfolobus acidocaldarius threads (0406) filament. To Be Published
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6AHR
| Cryo-EM structure of human Ribonuclease P | 分子名称: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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6YJB
| VcaM4I restriction endonuclease 5hmC-ssDNA complex | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*AP*(5HC)P*AP*G)-3'), GLYCEROL, ... | 著者 | Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M. | 登録日 | 2020-04-02 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA. Nucleic Acids Res., 49, 2021
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1AOY
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7W9W
| 2.02 angstrom cryo-EM structure of the pump-like channelrhodopsin ChRmine | 分子名称: | CHOLESTEROL, ChRmine, PALMITIC ACID, ... | 著者 | Kishi, K.E, Kim, Y, Fukuda, M, Yamashita, K, Deisseroth, K, Kato, H.E. | 登録日 | 2021-12-11 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine. Cell, 185, 2022
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1BA9
| THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES | 分子名称: | COPPER (I) ION, SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Banci, L, Benedetto, M, Bertini, I, Del Conte, R, Piccioli, M, Viezzoli, M.S. | 登録日 | 1998-04-24 | 公開日 | 1998-09-16 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?. Biochemistry, 37, 1998
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6MAJ
| HBO1 is required for the maintenance of leukaemia stem cells | 分子名称: | 4-fluoro-N'-[(3-hydroxyphenyl)sulfonyl]-5-methyl[1,1'-biphenyl]-3-carbohydrazide, BRD1 protein, GLYCEROL, ... | 著者 | Ren, B, Peat, T.S, Monahan, B, Dawson, M, Street, I. | 登録日 | 2018-08-27 | 公開日 | 2019-12-25 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (2.139 Å) | 主引用文献 | HBO1 is required for the maintenance of leukaemia stem cells. Nature, 577, 2020
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8RW3
| Crystal Structure of Agd31B, alpha-transglucosylase, complexed with a non-covalent 1,2- Cyclophellitol aziridine | 分子名称: | (1~{S},2~{R},3~{R},4~{R},6~{S})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, 1,2-ETHANEDIOL, OXALATE ION, ... | 著者 | Moran, E, Davies, G, Ofamn, T, Heming, J, Nin-Hill, A, Kullmer, F, Steneker, R, Klein, A, Bennett, M, Ruijgrok, G, Kok, K, Aerts, J, Van der Marel, G, Rovira, C, Artola, M, Codee, J, Overkleeft, H. | 登録日 | 2024-02-02 | 公開日 | 2024-05-15 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining alpha-Glucosidase Inhibition. Chemistry, 30, 2024
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7SNO
| Structure of Bacple_01701(H214N), a 6-O-galactose porphyran sulfatase | 分子名称: | 1,2-ETHANEDIOL, 6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, Arylsulfatase, ... | 著者 | Ulaganathan, T, Cygler, M. | 登録日 | 2021-10-28 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations Biorxiv, 2023
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7O8G
| NmHR light state structure at 10 ps after photoexcitation determined by serial femtosecond crystallography (with extrapolated, dark and light dataset) | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Chloride pumping rhodopsin, ... | 著者 | Mous, S, Gotthard, G, Ehrenberg, D, Sen, S, James, D, Johnson, P, Weinert, T, Nass, K, Furrer, A, Kekilli, D, Ma, P, Bruenle, S, Casadei, C, Martiel, I, Dworkowski, F, Gashi, D, Skopintsev, P, Wranik, M, Knopp, G, Panepucci, E, Panneels, V, Cirelli, C, Ozerov, D, Schertler, G, Wang, M, Milne, C, Standfuss, J, Schapiro, I, Heberle, J, Nogly, P. | 登録日 | 2021-04-15 | 公開日 | 2022-02-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Dynamics and mechanism of a light-driven chloride pump. Science, 375, 2022
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7O8Y
| Anomalous bromide substructure of NmHR under dark state conditions determined at 13.7 keV with serial crystallography | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, BROMIDE ION, Chloride pumping rhodopsin, ... | 著者 | Mous, S, Gotthard, G, Ehrenberg, D, Sen, S, James, D, Johnson, P, Weinert, T, Nass, K, Furrer, A, Kekilli, D, Ma, P, Bruenle, S, Casadei, C, Martiel, I, Dworkowski, F, Gashi, D, Skopintsev, P, Wranik, M, Knopp, G, Panepucci, E, Panneels, V, Cirelli, C, Ozerov, D, Schertler, G, Wang, M, Milne, C, Standfuss, J, Schapiro, I, Heberle, J, Nogly, P. | 登録日 | 2021-04-15 | 公開日 | 2022-02-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Dynamics and mechanism of a light-driven chloride pump. Science, 375, 2022
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7O8O
| NmHR light state structure at 12.5 ms (10 - 15 ms) after photoexcitation determined by serial millisecond crystallography | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Chloride pumping rhodopsin, OLEIC ACID, ... | 著者 | Mous, S, Gotthard, G, Ehrenberg, D, Sen, S, James, D, Johnson, P, Weinert, T, Nass, K, Furrer, A, Kekilli, D, Ma, P, Bruenle, S, Casadei, C, Martiel, I, Dworkowski, F, Gashi, D, Skopintsev, P, Wranik, M, Knopp, G, Panepucci, E, Panneels, V, Cirelli, C, Ozerov, D, Schertler, G, Wang, M, Milne, C, Standfuss, J, Schapiro, I, Heberle, J, Nogly, P. | 登録日 | 2021-04-15 | 公開日 | 2022-02-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Dynamics and mechanism of a light-driven chloride pump. Science, 375, 2022
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