6YMG

VcaM4I restriction endonuclease in complex with 5mC-modified dsDNA

Summary for 6YMG

• Entry DOI: 10.2210/pdb6ymg/pdb
• Related: 5J3E 6YEX 6YJB 6YKF
• Descriptor: HNH endonuclease, DNA (5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*A)-3'), DNA (5'-D(P*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), ... (6 entities in total)
• Functional Keywords: pua superfamily, eve domain, dna endonuclease, modification-dependent restriction endonuclease, mdre, 5-hydroxymethylcytosine, 5-methylcytosine, hydrolase
• Biological source: Vibrio campbellii; More
• Total number of polymer chains: 6
• Total formula weight: 85125.95

Authors

Pastor, M.,Czapinska, H.,Lutz, T.,Helbrecht, I.,Xu, S.,Bochtler, M. (deposition date: 2020-04-08, release date: 2020-12-23, Last modification date: 2024-01-24)

• Primary citation: Pastor, M.,Czapinska, H.,Helbrecht, I.,Krakowska, K.,Lutz, T.,Xu, S.Y.,Bochtler, M.; Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.; Nucleic Acids Res., 49:1708-1723, 2021; PubMed: 33450012; DOI: 10.1093/nar/gkaa1218

Experimental method

X-RAY DIFFRACTION (3.14 Å)