6LP1

Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei.

Summary for 6LP1

Entry DOI	10.2210/pdb6lp1/pdb
Descriptor	Succinyl-CoA:3-ketoacid-coenzyme A transferase, CALCIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	trypanosoma brucei, acetate:succinate coa transferase, mitochondrial enzyme, transferase
Biological source	Trypanosoma brucei
Total number of polymer chains	4
Total formula weight	207777.03
Authors	Mochizuki, K.,Inaoka, D.K.,Shiba, T.,Fukuda, K.,Kurasawa, H.,Mazet, M.,Millerioux, Y.,Bringaud, F.,Boshart, M.,Balogun, E.O.,Harada, S.,Hirayama, K.,Kita, K. (deposition date: 2020-01-08, release date: 2020-10-07, Last modification date: 2023-11-29)
Primary citation	Mochizuki, K.,Inaoka, D.K.,Mazet, M.,Shiba, T.,Fukuda, K.,Kurasawa, H.,Millerioux, Y.,Boshart, M.,Balogun, E.O.,Harada, S.,Hirayama, K.,Bringaud, F.,Kita, K. The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei. Biochim Biophys Acta Bioenerg, 1861:148283-148283, 2020 Cited by PubMed: 32763239 DOI: 10.1016/j.bbabio.2020.148283 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation