6LP1

Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
A	0008410	molecular_function	CoA-transferase activity
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding
A	0046950	biological_process	cellular ketone body metabolic process
A	0046952	biological_process	ketone body catabolic process
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
B	0008410	molecular_function	CoA-transferase activity
B	0016740	molecular_function	transferase activity
B	0046872	molecular_function	metal ion binding
B	0046950	biological_process	cellular ketone body metabolic process
B	0046952	biological_process	ketone body catabolic process
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
C	0008410	molecular_function	CoA-transferase activity
C	0016740	molecular_function	transferase activity
C	0046872	molecular_function	metal ion binding
C	0046950	biological_process	cellular ketone body metabolic process
C	0046952	biological_process	ketone body catabolic process
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
D	0008410	molecular_function	CoA-transferase activity
D	0016740	molecular_function	transferase activity
D	0046872	molecular_function	metal ion binding
D	0046950	biological_process	cellular ketone body metabolic process
D	0046952	biological_process	ketone body catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CA A 501

Chain	Residue
A	GLN211
A	ASP239

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site_id	AC2
Number of Residues	2
Details	binding site for residue CA B 501

Chain	Residue
B	GLN211
B	ASP239

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site_id	AC3
Number of Residues	2
Details	binding site for residue CA C 501

Chain	Residue
C	GLN211
C	ASP239

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site_id	AC4
Number of Residues	4
Details	binding site for residue GOL C 502

Chain	Residue
C	ASN173
C	ARG116
C	LEU171
C	GLU172

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site_id	AC5
Number of Residues	2
Details	binding site for residue CA D 501

Chain	Residue
D	GLN211
D	ASP239

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site_id	AC6
Number of Residues	5
Details	binding site for residue GOL D 502

Chain	Residue
D	ARG116
D	ARG159
D	LEU171
D	GLU172
D	ASN173

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Functional Information from PROSITE/UniProt

site_id	PS01273
Number of Residues	16
Details	COA_TRANSF_1 Coenzyme A transferases signature 1. NGatLAVGGFgtgGmP

Chain	Residue	Details
A	ASN27-PRO42

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site_id	PS01274
Number of Residues	9
Details	COA_TRANSF_2 Coenzyme A transferases signature 2. LQSENGLIG

Chain	Residue	Details
A	LEU316-GLY324

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