5YEG

Crystal structure of CTCF ZFs4-8-Hs5-1a complex

Summary for 5YEG

• Entry DOI: 10.2210/pdb5yeg/pdb
• Descriptor: Transcriptional repressor CTCF, DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3'), DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3'), ... (6 entities in total)
• Functional Keywords: zinc fingers, insulators, enhancers, promoters, 3d genome, topological domains, contact loops, higher-order chromatin structure, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 59322.31

Authors

Yin, M.,Wang, J.,Wang, M.,Li, X. (deposition date: 2017-09-17, release date: 2017-11-29, Last modification date: 2024-03-27)

• Primary citation: Yin, M.,Wang, J.,Wang, M.,Li, X.,Zhang, M.,Wu, Q.,Wang, Y.; Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites; Cell Res., 27:1365-1377, 2017; PubMed: 29076501; DOI: 10.1038/cr.2017.131

Experimental method

X-RAY DIFFRACTION (2 Å)