5YEG

Crystal structure of CTCF ZFs4-8-Hs5-1a complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcriptional repressor CTCF	polymer	142	16825.6	1	UniProt (P49711) Pfam (PF00096)	Homo sapiens (Human)	11-zinc finger protein,CCCTC-binding factor,CTCFL paralog
2	B (B)	Transcriptional repressor CTCF	polymer	141	16696.4	1	UniProt (P49711) Pfam (PF00096)	Homo sapiens (Human)	11-zinc finger protein,CCCTC-binding factor,CTCFL paralog
3	C, E (D, E)	DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3')	polymer	21	6405.1	2		synthetic construct
4	D, F (C, F)	DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3')	polymer	20	6168.0	2		synthetic construct
5	G, H, I, J, K... (A, B)	ZINC ION	non-polymer		65.4	10	Chemie (ZN)
6	Q, R, S, T, U... (A, B, D, C, E...)	water	water		18.0	607	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	58668.2
Non-Polymers*	Number of molecules	10
	Total formula weight	654.1
All*	Total formula weight	59322.3

*Water molecules are not included.