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4QBQ
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BU of 4qbq by Molmil
Crystal structure of DNMT3a ADD domain bound to H3 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
著者Li, H, Patel, D.J.
登録日2014-05-08
公開日2015-05-13
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
4QEN
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BU of 4qen by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA and SAH
分子名称: DNA (5'-D(*AP*CP*TP*GP*AP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*TP*CP*AP*GP*TP*AP*T)-3'), Histone-lysine N-methyltransferase, ...
著者Du, J, Li, S, Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4NTO
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BU of 4nto by Molmil
Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C2 ceramide-1-phosphate (d18:1/2:0) at 2.15 Angstrom resolution
分子名称: (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER, accelerated-cell-death 11
著者Simanshu, D.K, Brown, R.E, Patel, D.J.
登録日2013-12-02
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NT1
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BU of 4nt1 by Molmil
Crystal structure of apo-form of Arabidopsis ACD11 (accelerated-cell-death 11) at 1.8 Angstrom resolution
分子名称: SODIUM ION, accelerated-cell-death 11
著者Simanshu, D.K, Brown, R.E, Patel, D.J.
登録日2013-11-29
公開日2014-02-05
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTG
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BU of 4ntg by Molmil
Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C12 ceramide-1-phosphate (d18:1/12:0) at 2.55 Angstrom resolution
分子名称: (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, accelerated-cell-death 11
著者Simanshu, D.K, Brown, R.E, Patel, D.J.
登録日2013-12-02
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5505 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTI
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BU of 4nti by Molmil
Crystal structure of D60N mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C12 ceramide-1-phosphate (d18:1/12:0) at 2.9 Angstrom resolution
分子名称: (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER, accelerated-cell-death 11
著者Simanshu, D.K, Brown, R.E, Patel, D.J.
登録日2013-12-02
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4ONJ
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BU of 4onj by Molmil
Crystal structure of the catalytic domain of ntDRM
分子名称: DNA methyltransferase, SINEFUNGIN
著者Du, J, Patel, D.J.
登録日2014-01-28
公開日2014-06-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.807 Å)
主引用文献Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
4QXB
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BU of 4qxb by Molmil
crystal structure of histone demethylase KDM2A-H3K36ME3 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXR
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BU of 4qxr by Molmil
Crystal structure of hSTING(S162A/G230I/Q266I) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QWN
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BU of 4qwn by Molmil
Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-16
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXQ
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BU of 4qxq by Molmil
Crystal structure of hSTING(S162A/Q266I) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QX8
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BU of 4qx8 by Molmil
Crystal structure of histone demethylase kdm2a-h3k36me3 complex with alpha-kg
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXH
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BU of 4qxh by Molmil
Crystal structure of histone demethylase KDM2A-H3K36ME1 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-20
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QEP
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BU of 4qep by Molmil
crystal structure of KRYPTONITE in complex with mCHG DNA and SAH
分子名称: DNA (5'-D(*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*TP*AP*T)-3'), Histone-lysine N-methyltransferase, ...
著者Du, J, Li, S, Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4QX7
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BU of 4qx7 by Molmil
Crystal structure of histone demethylase kdm2a-h3k36me2 with alpha-kg
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-18
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXP
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BU of 4qxp by Molmil
Crystal structure of hSTING(G230I) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QLN
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BU of 4qln by Molmil
structure of ydao riboswitch binding with c-di-dAMP
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, RNA (117-MER)
著者Ren, A.M, Patel, D.J.
登録日2014-06-12
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat.Chem.Biol., 10, 2014
4QXC
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BU of 4qxc by Molmil
Crystal structure of histone demethylase KDM2A-H3K36ME2 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXO
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BU of 4qxo by Molmil
Crystal structure of hSTING(group2) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4NH3
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BU of 4nh3 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 13-mer siRNA having 5'-pU and UU-3' ends (2.6 Angstrom resolution)
分子名称: 5'-R(P*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
著者Simanshu, D.K, Tian, Y, Patel, D.J.
登録日2013-11-04
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.616 Å)
主引用文献A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4QEO
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BU of 4qeo by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
分子名称: DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ...
著者Du, J, Li, S, Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4IUP
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BU of 4iup by Molmil
crystal structure of Se-substituted arabidopsis thaliana SHH1 SAWADEE domain L200M/L218M mutant
分子名称: BETA-MERCAPTOETHANOL, CYMAL-4, SAWADEE HOMEODOMAIN HOMOLOG 1, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUV
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BU of 4iuv by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide
分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUT
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BU of 4iut by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide
分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IX7
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Crystal Structure of the insv-BEN domain complexed to its DNA target site
分子名称: 5'-D(*GP*TP*TP*CP*CP*AP*AP*TP*TP*GP*GP*AP*A)-3', RE55538p
著者Ren, A, Serganov, A, Patel, D.J.
登録日2013-01-24
公開日2013-03-20
最終更新日2013-04-03
実験手法X-RAY DIFFRACTION (1.581 Å)
主引用文献The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors.
Genes Dev., 27, 2013

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