4NTG

Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C12 ceramide-1-phosphate (d18:1/12:0) at 2.55 Angstrom resolution

Summary for 4NTG

• Entry DOI: 10.2210/pdb4ntg/pdb
• Related: 4NT1 4NT2 4NTI 4NTO
• Descriptor: accelerated-cell-death 11, (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (3 entities in total)
• Functional Keywords: protein-lipid complexes, gltp-fold, lipid transfer protein, cell death, ceramide-1-phosphate, c1p, transport protein
• Biological source: Arabidopsis thaliana (mouse-ear cress)
• Total number of polymer chains: 2
• Total formula weight: 46630.49

Authors

Simanshu, D.K.,Brown, R.E.,Patel, D.J. (deposition date: 2013-12-02, release date: 2014-02-05, Last modification date: 2023-09-20)

• Primary citation: Simanshu, D.K.,Zhai, X.,Munch, D.,Hofius, D.,Markham, J.E.,Bielawski, J.,Bielawska, A.,Malinina, L.,Molotkovsky, J.G.,Mundy, J.W.,Patel, D.J.,Brown, R.E.; Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.; Cell Rep, 6:388-399, 2014; PubMed: 24412362; DOI: 10.1016/j.celrep.2013.12.023

Experimental method

X-RAY DIFFRACTION (2.5505 Å)