4NTG

Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C12 ceramide-1-phosphate (d18:1/12:0) at 2.55 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006869	biological_process	lipid transport
A	0008289	molecular_function	lipid binding
A	0009751	biological_process	response to salicylic acid
A	0015914	biological_process	phospholipid transport
A	0035627	biological_process	ceramide transport
A	0042742	biological_process	defense response to bacterium
A	0120009	biological_process	intermembrane lipid transfer
A	0120013	molecular_function	lipid transfer activity
A	0120014	molecular_function	phospholipid transfer activity
A	0120016	molecular_function	sphingolipid transfer activity
A	0140338	molecular_function	sphingomyelin transfer activity
A	1902387	molecular_function	ceramide 1-phosphate binding
A	1902388	molecular_function	ceramide 1-phosphate transfer activity
A	1902389	biological_process	ceramide 1-phosphate transport
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006869	biological_process	lipid transport
B	0008289	molecular_function	lipid binding
B	0009751	biological_process	response to salicylic acid
B	0015914	biological_process	phospholipid transport
B	0035627	biological_process	ceramide transport
B	0042742	biological_process	defense response to bacterium
B	0120009	biological_process	intermembrane lipid transfer
B	0120013	molecular_function	lipid transfer activity
B	0120014	molecular_function	phospholipid transfer activity
B	0120016	molecular_function	sphingolipid transfer activity
B	0140338	molecular_function	sphingomyelin transfer activity
B	1902387	molecular_function	ceramide 1-phosphate binding
B	1902388	molecular_function	ceramide 1-phosphate transfer activity
B	1902389	biological_process	ceramide 1-phosphate transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE 1PZ A 301

Chain	Residue
A	ALA53
A	PHE139
A	HIS143
A	ILE147
A	ALA150
A	VAL151
A	LEU153
A	HOH401
A	HOH403
A	HOH406
A	HOH409
A	PHE54
A	HOH412
B	GLY144
A	ALA57
A	ALA60
A	TYR61
A	LYS64
A	ARG99
A	ARG103
A	MET110

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 1PZ B 301

Chain	Residue
A	GLY144
B	ALA53
B	ALA57
B	LYS64
B	ARG99
B	ARG103
B	MET110
B	PHE139
B	HIS143
B	ILE147
B	ALA150
B	LEU153
B	HOH404
B	HOH412
B	HOH421

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:24412362

Chain	Residue	Details
A	ALA60
B	HIS143
A	LYS64
A	ARG99
A	ARG103
A	HIS143
B	ALA60
B	LYS64
B	ARG99
B	ARG103

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