6VIE
| Structure of caspase-1 in complex with gasdermin D | 分子名称: | Caspase-1 subunit p10, Caspase-1 subunit p20, Gasdermin-D | 著者 | Liu, Z, Xiao, T.S. | 登録日 | 2020-01-13 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage. Immunity, 53, 2020
|
|
6RNW
| |
5GZR
| Zika virus E protein complexed with a neutralizing antibody Z23-Fab | 分子名称: | Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ... | 著者 | Gao, G.G, Shi, Y, Peng, R, Liu, S. | 登録日 | 2016-10-01 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
|
|
6R46
| |
6R48
| |
6RNV
| |
7NRJ
| |
7O5T
| |
7O5N
| Crystal Structure of a Class D carbapenemase complexed with Avibactam | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1-BUTANOL, Beta-lactamase, ... | 著者 | Zhou, Q, Zhang, Z, He, Y, Jin, Y. | 登録日 | 2021-04-09 | 公開日 | 2022-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
|
|
7F7W
| JAK2-JH2 | 分子名称: | 2-((1-(2-fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl)(methyl)amino)ethan-1-ol, Tyrosine-protein kinase JAK2 | 著者 | Niu, L. | 登録日 | 2021-06-30 | 公開日 | 2022-03-30 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2 V617F -induced myeloproliferative neoplasms. Blood Cancer J, 12, 2022
|
|
7O9N
| |
4P6X
| Crystal Structure of cortisol-bound glucocorticoid receptor ligand binding domain | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Glucocorticoid receptor, Nuclear receptor coactivator 2 | 著者 | He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. | 登録日 | 2014-03-25 | 公開日 | 2014-04-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
|
|
7PB8
| Crystal structure of the CENP-OPQUR complex | 分子名称: | Centromere protein O, Centromere protein P, Centromere protein Q, ... | 著者 | Bellini, D, Yatskevich, S, Muir, K.W, Barford, D. | 登録日 | 2021-07-31 | 公開日 | 2022-04-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.68 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
|
|
7PB4
| Cenp-HIK 3-protein complex | 分子名称: | Centromere protein H, Centromere protein I, Centromere protein K | 著者 | Bellini, D, Yatskevich, S, Muir, W.K, Barford, D. | 登録日 | 2021-07-30 | 公開日 | 2022-04-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
|
|
7OJ2
| Bacillus subtilis IMPDH in complex with Ap4A | 分子名称: | GLYCEROL, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION | 著者 | Giammarinaro, P.I, Bange, G. | 登録日 | 2021-05-13 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
|
|
7OJ1
| |
7PKN
| Structure of the human CCAN deltaCT complex | 分子名称: | Centromere protein H, Centromere protein I, Centromere protein K, ... | 著者 | Muir, K.W, Yatskevich, S, Bellini, D, Barford, D. | 登録日 | 2021-08-25 | 公開日 | 2022-04-27 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
|
|
4P6W
| Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain | 分子名称: | Glucocorticoid receptor, MOMETASONE FUROATE, Nuclear receptor coactivator 2 | 著者 | He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. | 登録日 | 2014-03-25 | 公開日 | 2014-04-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | 主引用文献 | Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
|
|
6NPU
| |
8PPR
| |
8QNZ
| Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem | 分子名称: | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, 1-BUTANOL, BROMIDE ION, ... | 著者 | Zhou, Q, He, Y, Jin, Y. | 登録日 | 2023-09-27 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity. Acs Cent.Sci., 9, 2023
|
|
8Q85
| |
8Q84
| |
8QAU
| |
6JLQ
| Crystal structure of human USP46-WDR48-WDR20 complex | 分子名称: | GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ... | 著者 | Zhu, H, Zhang, T, Ding, J. | 登録日 | 2019-03-06 | 公開日 | 2019-07-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | 主引用文献 | Structural insights into the activation of USP46 by WDR48 and WDR20. Cell Discov, 5, 2019
|
|