7O5T

OXA-48 with carbamylated Lys73 in complex with bromide ions at neutral pH

This is a non-PDB format compatible entry.

Summary for 7O5T

• Entry DOI: 10.2210/pdb7o5t/pdb
• Descriptor: Beta-lactamase, BROMIDE ION (3 entities in total)
• Functional Keywords: oxa, apo, bromide, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 4
• Total formula weight: 121815.57

Authors

Zhou, Q.,He, Y.,Jin, Y. (deposition date: 2021-04-09, release date: 2022-04-20, Last modification date: 2025-08-06)

• Primary citation: Zhou, Q.,Catalan, P.,Bell, H.,Baumann, P.,Cooke, R.,Evans, R.,Yang, J.,Zhang, Z.,Zappala, D.,Zhang, Y.,Blackburn, G.M.,He, Y.,Jin, Y.; An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity; Acs Cent.Sci., 2023; DOI: 10.1021/acscentsci.3c00609

Experimental method

X-RAY DIFFRACTION (1.81 Å)