8QNZ
Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem
This is a non-PDB format compatible entry.
Summary for 8QNZ
Entry DOI | 10.2210/pdb8qnz/pdb |
Descriptor | Beta-lactamase, (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, BROMIDE ION, ... (5 entities in total) |
Functional Keywords | oxa, imipenem, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 4 |
Total formula weight | 122921.68 |
Authors | |
Primary citation | Zhou, Q.,Catalan, P.,Bell, H.,Baumann, P.,Cooke, R.,Evans, R.,Yang, J.,Zhang, Z.,Zappala, D.,Zhang, Y.,Blackburn, G.M.,He, Y.,Jin, Y. An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity. Acs Cent.Sci., 9:2339-2349, 2023 Cited by PubMed: 38161376DOI: 10.1021/acscentsci.3c00609 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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