8QNZ

Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB, CCC, DDD	Beta-lactamase	polymer	260	30254.1	4	UniProt (Q6XEC0) Pfam (PF00905) In PDB	Klebsiella pneumoniae
2	AAA, BBB, DDD	(2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid	non-polymer		317.4	3	Chemie (8YF)
3	AAA, BBB, CCC, DDD	BROMIDE ION	non-polymer		79.9	11	Chemie (BR)
4	BBB	1-BUTANOL	non-polymer		74.1	1	Chemie (1BO)
5		water	water		18.0	1019	Chemie (HOH)

Sequence modifications

AAA, BBB, CCC, DDD: 23 - 265 (UniProt: Q6XEC0)

PDB	External Database	Details
Met 6	-	initiating methionine
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 13	-	expression tag
Ala 14	-	expression tag
Gly 15	-	expression tag
Glu 16	-	expression tag
Asn 17	-	expression tag
Leu 18	-	expression tag
Tyr 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag
Gly 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	121016.5
Non-Polymers*	Number of molecules	15
	Total formula weight	1905.1
All*	Total formula weight	122921.7

*Water molecules are not included.