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4J4F
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BU of 4j4f by Molmil
Structure of P51G Cyanovirin-N swapped tetramer in the P212121 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
8KAG
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BU of 8kag by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and target RNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, RNA (5'-R(*CP*CP*AP*CP*UP*UP*CP*AP*AP*UP*UP*AP*GP*AP*AP*CP*AP*CP*GP*GP*AP*CP*C)-3'), RNA (98-MER)
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAK
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BU of 8kak by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 18nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAJ
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BU of 8kaj by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*TP*TP*TP*AP*TP*CP*CP*AP*TP*AP*AP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAH
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BU of 8kah by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 18nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAI
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BU of 8kai by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 17nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
4GM3
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BU of 4gm3 by Molmil
Crystal structure of human WD repeat domain 5 with compound MM-101
分子名称: MM-101, WD repeat-containing protein 5
著者Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Cao, F, Liu, L, Lei, M, Dou, Y, Wang, S.
登録日2012-08-15
公開日2013-07-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.393 Å)
主引用文献High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
J.Am.Chem.Soc., 135, 2013
8KAM
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BU of 8kam by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.91 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAL
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BU of 8kal by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 17nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
4J4C
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BU of 4j4c by Molmil
Structure of P51G Cyanovirin-N swapped dimer in the P3221 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4D
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BU of 4j4d by Molmil
Structure of P51G Cyanovirin-N swapped dimer in the P21212 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GM9
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BU of 4gm9 by Molmil
Crystal structure of human WD repeat domain 5 with compound MM-401
分子名称: MM-401, WD repeat-containing protein 5
著者Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Liu, L, Dou, Y, Lei, M, Wang, S.
登録日2012-08-15
公開日2014-02-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human WD repeat domain 5 with compound MM-401
To be Published
5YEI
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BU of 5yei by Molmil
Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase
分子名称: Aspartokinase, GLYCEROL, LYSINE, ...
著者Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R.
登録日2017-09-17
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase.
Biochem.J., 475, 2018
7YQK
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BU of 7yqk by Molmil
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1
分子名称: DNA (145-MER), Histone H2AX, Histone H2B, ...
著者Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L.
登録日2022-08-07
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.
J.Am.Chem.Soc., 144, 2022
4IC6
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BU of 4ic6 by Molmil
Crystal structure of Deg8
分子名称: Protease Do-like 8, chloroplastic
著者Gong, W, Sun, W, Fan, H, Gao, F, Liu, L.
登録日2012-12-10
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
7VW2
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BU of 7vw2 by Molmil
Structure of a dimeric periplasmic protein bound with cupric ions
分子名称: COPPER (II) ION, DUF305 domain-containing protein
著者Yang, J, Liu, L.
登録日2021-11-09
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.186 Å)
主引用文献Structural basis of copper binding by a dimeric periplasmic protein forming a six-helical bundle.
J.Inorg.Biochem., 229, 2022
7VW1
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BU of 7vw1 by Molmil
Structure of a dimeric periplasmic protein bound with cuprous ions
分子名称: COPPER (I) ION, DUF305 domain-containing protein
著者Yang, J, Liu, L.
登録日2021-11-09
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Structural basis of copper binding by a dimeric periplasmic protein forming a six-helical bundle.
J.Inorg.Biochem., 229, 2022
7VW0
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BU of 7vw0 by Molmil
Structure of a dimeric periplasmic protein
分子名称: DUF305 domain-containing protein
著者Yang, J, Liu, L.
登録日2021-11-09
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.447 Å)
主引用文献Structural basis of copper binding by a dimeric periplasmic protein forming a six-helical bundle.
J.Inorg.Biochem., 229, 2022
7WH1
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BU of 7wh1 by Molmil
structure of C elegans BCMO-2
分子名称: Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ...
著者Pan, W, Liu, L.
登録日2021-12-29
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans .
Front Mol Biosci, 9, 2022
7WH0
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BU of 7wh0 by Molmil
structure of C elegans BCMO-1
分子名称: Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ...
著者Pan, W, Liu, L.
登録日2021-12-29
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans .
Front Mol Biosci, 9, 2022
6IYA
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BU of 6iya by Molmil
Structure of the DNA binding domain of antitoxin CopASO
分子名称: Transcriptional regulator CopG family
著者Zhao, R, Li, F, Liu, L, Zhang, X.
登録日2018-12-14
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and allosteric coupling of type II antitoxin CopASO.
Biochem.Biophys.Res.Commun., 514, 2019
4IC5
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BU of 4ic5 by Molmil
Crystal structure of Deg5
分子名称: CALCIUM ION, Protease Do-like 5, chloroplastic
著者Gong, W, Sun, W, Fan, H, Gao, F, Liu, L.
登録日2012-12-10
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.607 Å)
主引用文献The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
5Z9X
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BU of 5z9x by Molmil
Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate
分子名称: MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ...
著者Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J.
登録日2018-02-05
公開日2018-06-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
7CRD
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BU of 7crd by Molmil
Structure of Pseudomonas aeruginosa OdaA
分子名称: Probable enoyl-CoA hydratase/isomerase
著者Zhao, N, Zhao, C, Liu, L, Li, T, Li, C, He, L, Zhu, Y, Song, Y, Bao, R.
登録日2020-08-13
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structural and molecular dynamic studies of Pseudomonas aeruginosa OdaA reveal the regulation role of a C-terminal hinge element.
Biochim Biophys Acta Gen Subj, 1865, 2020
4MQU
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BU of 4mqu by Molmil
Human GKRP complexed to AMG-3969 and S6P
分子名称: 2-{4-[(2S)-4-[(6-aminopyridin-3-yl)sulfonyl]-2-(prop-1-yn-1-yl)piperazin-1-yl]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ...
著者St Jean, D.J, Ashton, K.S, Bartberger, M.D, Chen, J, Chmait, S, Cupples, R, Galbreath, E, Helmering, J, Jordan, S.R, Liu, L.
登録日2013-09-16
公開日2014-05-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
J.Med.Chem., 57, 2014

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