7YQK
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1
Summary for 7YQK
Entry DOI | 10.2210/pdb7yqk/pdb |
EMDB information | 34028 |
Descriptor | Histone H3.1, Histone H4, Histone H2AX, ... (9 entities in total) |
Functional Keywords | nucleosoeme, 53bp1, complex, h4k20me2, h2axk15ub, gammah2ax, nuclear protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 13 |
Total formula weight | 201815.41 |
Authors | Ai, H.S.,GuoChao, C.,Qingyue, G.,Ze-Bin, T.,Zhiheng, D.,Xin, L.,Fan, Y.,Ziyu, X.,Jia-Bin, L.,Changlin, T.,Liu, L. (deposition date: 2022-08-07, release date: 2022-08-17, Last modification date: 2024-07-03) |
Primary citation | Ai, H.,Chu, G.C.,Gong, Q.,Tong, Z.B.,Deng, Z.,Liu, X.,Yang, F.,Xu, Z.,Li, J.B.,Tian, C.,Liu, L. Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes. J.Am.Chem.Soc., 144:18329-18337, 2022 Cited by PubMed: 36166692DOI: 10.1021/jacs.2c06156 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.38 Å) |
Structure validation
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