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8E3E
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BU of 8e3e by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#10)
分子名称: DNA (5'-D(*CP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*A)-3'), ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2022-08-17
公開日2023-02-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
8F8Y
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BU of 8f8y by Molmil
PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
8F8Z
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BU of 8f8z by Molmil
PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
4E12
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BU of 4e12 by Molmil
Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase
分子名称: Diketoreductase, GLYCEROL, PENTAETHYLENE GLYCOL, ...
著者Lu, M, White, M.A, Huang, Y, Wu, X, Liu, N, Cheng, X, Chen, Y.
登録日2012-03-05
公開日2012-11-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase
Chem.Commun.(Camb.), 48, 2012
4WOQ
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BU of 4woq by Molmil
Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric
分子名称: 2-KETOBUTYRIC ACID, N-acetylneuraminate lyase
著者Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M.
登録日2014-10-16
公開日2015-10-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric
to be published
4WOZ
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BU of 4woz by Molmil
Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
分子名称: 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, N-acetylneuraminate lyase
著者Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M.
登録日2014-10-17
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
to be published
7M10
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PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1
分子名称: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ...
著者Horton, J.R, Cheng, X.
登録日2021-03-11
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Biochem.J., 478, 2021
1C8J
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BU of 1c8j by Molmil
CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F)
分子名称: CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
著者Liu, Y, Jiang, F, Guo, Q, Chen, X, Jin, J, Sun, Y, Rao, Z.
登録日2000-05-31
公開日2001-05-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F)
To be Published
1QET
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BU of 1qet by Molmil
TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*AP*UP*GP*UP*CP*C)-3')
著者Mcdowell, J.A, He, L, Chen, X, Turner, D.H.
登録日1997-03-04
公開日1997-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2.
Biochemistry, 36, 1997
1R1V
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BU of 1r1v by Molmil
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the Zn2-form
分子名称: ZINC ION, repressor protein
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R22
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BU of 1r22 by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB (C14S/C61S/C121S mutant) in the Zn2alpha5-form
分子名称: Transcriptional repressor smtB, ZINC ION
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1QES
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BU of 1qes by Molmil
TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*AP*GP*UP*UP*CP*C)-3')
著者Mcdowell, J.A, He, L, Chen, X, Turner, D.H.
登録日1997-03-04
公開日1997-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2.
Biochemistry, 36, 1997
5WWM
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BU of 5wwm by Molmil
Crystal structure of the TPR domain of Rrp5
分子名称: SULFATE ION, rRNA biogenesis protein RRP5
著者Ye, K, Chen, X.
登録日2017-01-03
公開日2017-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Correction: Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
7SGL
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BU of 7sgl by Molmil
DNA-PK complex of DNA end processing
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ...
著者Liu, L, Li, J, Chen, X, Yang, W, Gellert, M.
登録日2021-10-06
公開日2022-01-12
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
7SH1
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BU of 7sh1 by Molmil
Class II UvrA protein - Ecm16
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Excinuclease ABC subunit UvrA, ...
著者Grade, P, Erlandson, A, Ullah, A, Mathews, I.I, Chen, X, Kim, C.-Y, Mera, P.E.
登録日2021-10-07
公開日2022-10-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi.
Sci Rep, 13, 2023
1R1T
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BU of 1r1t by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form
分子名称: Transcriptional repressor smtB
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1S8K
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BU of 1s8k by Molmil
Solution Structure of BmKK4, A Novel Potassium Channel Blocker from Scorpion Buthus martensii Karsch, 25 structures
分子名称: Toxin BmKK4
著者Zhang, N, Chen, X, Li, M, Cao, C, Wang, Y, Hu, G, Wu, H.
登録日2004-02-02
公開日2005-02-08
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of BmKK4, the first member of subfamily alpha-KTx 17 of scorpion toxins
Biochemistry, 43, 2004
1R1U
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BU of 1r1u by Molmil
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the apo-form
分子名称: repressor protein
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R23
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BU of 1r23 by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the Zn1-form (one Zn(II) per dimer)
分子名称: Transcriptional repressor smtB, ZINC ION
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
5X07
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BU of 5x07 by Molmil
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
分子名称: DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta
著者Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y.
登録日2017-01-20
公開日2017-08-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site
Biochemistry, 56, 2017
2AOC
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BU of 2aoc by Molmil
Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2005-08-12
公開日2006-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
2AOG
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BU of 2aog by Molmil
Crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog P2-NC
分子名称: ACETIC ACID, GLYCEROL, HIV-1 PROTEASE (RETROPEPSIN), ...
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2005-08-12
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
2AOD
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Crystal structure analysis of HIV-1 protease with a substrate analog P2-NC
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, HIV-1 PROTEASE, ...
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2005-08-12
公開日2006-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
5ESW
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BU of 5esw by Molmil
Crystal structure of Apo hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila
分子名称: PHOSPHATE ION, Purine/pyrimidine phosphoribosyltransferase
著者Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H.
登録日2015-11-17
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
5ESX
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Crystal structure of hypoxanthine-guanine phosphoribosyltransferase complexed with GMP from Legionella pneumophila
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Purine/pyrimidine phosphoribosyltransferase
著者Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H.
登録日2015-11-17
公開日2016-03-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016

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