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7D9M
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BU of 7d9m by Molmil
grass carp interleukin-2
分子名称: Interleukin
著者Junya, w, Jun, z.
登録日2020-10-13
公開日2020-10-28
最終更新日2020-11-11
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural insights into the co-evolution of IL-2 and its private receptor in fish.
Dev.Comp.Immunol., 115, 2020
5WES
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BU of 5wes by Molmil
Crystal Structure H2-Dd with disulfide-linked 5mer peptide
分子名称: Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ...
著者Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2017-07-10
公開日2017-10-18
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.706 Å)
主引用文献Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
7WRX
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BU of 7wrx by Molmil
Structure of Deinococcus radiodurans HerA-ADP complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, HerA, MAGNESIUM ION
著者Cheng, K.
登録日2022-01-27
公開日2023-02-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.40003562 Å)
主引用文献Structural and DNA end resection study of the bacterial NurA-HerA complex.
Bmc Biol., 21, 2023
3K5V
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BU of 3k5v by Molmil
Structure of Abl kinase in complex with imatinib and GNF-2
分子名称: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, ...
著者Cowan-Jacob, S.W, Fendrich, G, Rummel, G, Strauss, A.
登録日2009-10-08
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature, 463, 2010
6S35
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BU of 6s35 by Molmil
LSD1/CoREST1 complex with macrocyclic peptide inhibitor
分子名称: ALA-ARG-(D)LYS-MET-GLN-GLU-ALA-ARG-LYS-SER-THR, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ...
著者Talibov, V.O, Dobritzsch, D.
登録日2019-06-24
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1.
Acs Omega, 5, 2020
5WEU
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BU of 5weu by Molmil
Crystal Structure of H2-Dd with disulfide-linked 10mer peptide
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, Envelope glycoprotein gp160, ...
著者Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2017-07-10
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.584 Å)
主引用文献Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WET
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BU of 5wet by Molmil
Crystal Structure of H2-Dd with disulfide-linked 6mer peptide
分子名称: Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ...
著者Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2017-07-10
公開日2017-10-18
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WER
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BU of 5wer by Molmil
Crystal Structure of TAPBPR and H2-Dd complex
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ...
著者Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2017-07-10
公開日2017-10-18
最終更新日2019-08-28
実験手法X-RAY DIFFRACTION (3.412 Å)
主引用文献Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WPA
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BU of 5wpa by Molmil
Structure of human SFPQ/PSPC1 heterodimer
分子名称: Paraspeckle component 1, Splicing factor, proline- and glutamine-rich
著者Lee, M.
登録日2017-08-04
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins.
J. Biol. Chem., 293, 2018
5NNZ
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BU of 5nnz by Molmil
Crystal structure of human ODA16
分子名称: Dynein assembly factor with WDR repeat domains 1
著者Lorentzen, E, Taschner, T, Basquin, J.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Purification and crystal structure of human ODA16: Implications for ciliary import of outer dynein arms by the intraflagellar transport machinery.
Protein Sci., 29, 2020
6D8E
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BU of 6d8e by Molmil
Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor
分子名称: (4-fluorophenyl)methyl {2-[(1-methyl-1H-pyrazol-3-yl)amino]pyrimidin-4-yl}[3-(propanoylamino)phenyl]carbamate, Epidermal growth factor receptor
著者Park, E, Eck, M.J.
登録日2018-04-26
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.537 Å)
主引用文献Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor.
Angew. Chem. Int. Ed. Engl., 57, 2018
5I23
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BU of 5i23 by Molmil
Crystal Structure of Agd31B, alpha-transglucosylase in Glycoside Hydrolase Family 31, in complex with Cyclophellitol Aziridine probe CF022
分子名称: 1,2-ETHANEDIOL, 1-(8-{[(1S,2R,3S,4S,5R,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)cyclohexyl]amino}octyl)triaza-1,2-dien-2-ium, Oligosaccharide 4-alpha-D-glucosyltransferase, ...
著者Wu, L, Davies, G.J.
登録日2016-02-08
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Detection of Active Mammalian GH31 alpha-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes.
Acs Cent.Sci., 2, 2016
5I24
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BU of 5i24 by Molmil
Crystal Structure of Agd31B, alpha-transglucosylase in Glycoside Hydrolase Family 31, in complex with Cyclophellitol Aziridine probe CF021
分子名称: (1R,2S,3S,4R,5S,6R)-5-amino-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Wu, L, Davies, G.J.
登録日2016-02-08
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Detection of Active Mammalian GH31 alpha-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes.
Acs Cent.Sci., 2, 2016
5OMZ
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BU of 5omz by Molmil
Solution structure of domain III (DIII)of Zika virus Envelope protein
分子名称: Envelope Protein
著者Zerbe, O, Bardelli, M.
登録日2017-08-02
公開日2017-10-04
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
4CCP
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BU of 4ccp by Molmil
X-RAY STRUCTURES OF RECOMBINANT YEAST CYTOCHROME C PEROXIDASE AND THREE HEME-CLEFT MUTANTS PREPARED BY SITE-DIRECTED MUTAGENESIS
分子名称: PROTOPORPHYRIN IX CONTAINING FE, YEAST CYTOCHROME C PEROXIDASE
著者Wang, J, Mauro, J.M, Edwards, S.L, Oatley, S.J, Fishel, L.A, Ashford, V.A, Xuong, N.-H, Kraut, J.
登録日1990-02-28
公開日1991-07-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structures of recombinant yeast cytochrome c peroxidase and three heme-cleft mutants prepared by site-directed mutagenesis.
Biochemistry, 29, 1990
2PX9
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BU of 2px9 by Molmil
The intrinsic affinity between E2 and the Cys domain of E1 in Ubiquitin-like modifications
分子名称: SUMO-activating enzyme subunit 2, SUMO-conjugating enzyme UBC9
著者Wang, J.H, Hu, W.D, Cai, S, Lee, B, Song, J, Chen, Y.
登録日2007-05-14
公開日2007-07-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.
Mol.Cell, 27, 2007
4ZHK
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BU of 4zhk by Molmil
Crystal structure of RPE65 in complex with MB-002
分子名称: (1R)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, (1S)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, FE (II) ION, ...
著者Kiser, P.D, Palczewski, K.
登録日2015-04-25
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
5KMZ
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BU of 5kmz by Molmil
Solution NMR structure of Tetrahymena telomerase RNA pseudoknot
分子名称: Telomerase RNA pseudoknot
著者Cash, D.D, Feigon, J.
登録日2016-06-27
公開日2016-10-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
2CCP
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BU of 2ccp by Molmil
X-RAY STRUCTURES OF RECOMBINANT YEAST CYTOCHROME C PEROXIDASE AND THREE HEME-CLEFT MUTANTS PREPARED BY SITE-DIRECTED MUTAGENESIS
分子名称: PROTOPORPHYRIN IX CONTAINING FE, YEAST CYTOCHROME C PEROXIDASE
著者Wang, J, Mauro, J.M, Edwards, S.L, Oatley, S.J, Fishel, L.A, Ashford, V.A, Xuong, N.-H, Kraut, J.
登録日1990-02-28
公開日1991-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structures of recombinant yeast cytochrome c peroxidase and three heme-cleft mutants prepared by site-directed mutagenesis.
Biochemistry, 29, 1990
1K6Y
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BU of 1k6y by Molmil
Crystal Structure of a Two-Domain Fragment of HIV-1 Integrase
分子名称: Integrase, PHOSPHATE ION, POTASSIUM ION, ...
著者Wang, J, Ling, H, Yang, W, Craigie, R.
登録日2001-10-17
公開日2001-12-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.
EMBO J., 20, 2001
8TGP
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BU of 8tgp by Molmil
Crystal structure of SIRT2 with FAM-PEG4-H4K16(myristoyl) peptide
分子名称: H4K16(myristoyl) peptide, MYRISTIC ACID, NAD-dependent protein deacetylase sirtuin-2, ...
著者Nicely, N.I, Weiser, B.P.
登録日2023-07-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Effects of Dimerization on the Deacylase Activities of Human SIRT2.
Biochemistry, 62, 2023
5Y0A
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BU of 5y0a by Molmil
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
分子名称: protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
著者Wang, J.Q, Lok, S.M.
登録日2017-07-15
公開日2017-10-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
2NNX
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BU of 2nnx by Molmil
Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase
分子名称: SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Schuermann, J.P, Hart, P.J.
登録日2006-10-24
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability
J.Biol.Chem., 282, 2007
2FGF
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BU of 2fgf by Molmil
THREE-DIMENSIONAL STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR, A STRUCTURAL HOMOLOG OF INTERLEUKIN 1BETA
分子名称: HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR, SULFATE ION
著者Zhang, J, Sprang, S.R.
登録日1991-02-19
公開日1992-01-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.
Proc.Natl.Acad.Sci.USA, 88, 1991
2XVO
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BU of 2xvo by Molmil
SSO1725, a protein involved in the CRISPR/Cas pathway
分子名称: BETA-MERCAPTOETHANOL, SSO1725, SULFATE ION
著者Reeks, J, Liu, H, Naismith, J, White, M, McMahon, S.
登録日2010-10-26
公開日2010-12-29
最終更新日2014-02-05
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structure and Mechanism of the Cmr Complex for Crispr-Mediated Antiviral Immunity.
Mol.Cell, 45, 2012

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