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4ZHK

Crystal structure of RPE65 in complex with MB-002

Summary for 4ZHK
Entry DOI10.2210/pdb4zhk/pdb
DescriptorRetinoid isomerohydrolase, FE (II) ION, TETRAETHYLENE GLYCOL, ... (8 entities in total)
Functional Keywords7-bladed beta propeller, monotopic membrane protein, non-heme iron protein, retinoid isomerase, smooth endoplasmic reticulum, isomerase, hydrolase
Biological sourceBos taurus (Bovine)
Total number of polymer chains2
Total formula weight123924.16
Authors
Kiser, P.D.,Palczewski, K. (deposition date: 2015-04-25, release date: 2015-05-27, Last modification date: 2023-09-27)
Primary citationZhang, J.,Kiser, P.D.,Badiee, M.,Palczewska, G.,Dong, Z.,Golczak, M.,Tochtrop, G.P.,Palczewski, K.
Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125:2781-2794, 2015
Cited by
PubMed: 26075817
DOI: 10.1172/JCI80950
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.09 Å)
Structure validation

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