5I23

Crystal Structure of Agd31B, alpha-transglucosylase in Glycoside Hydrolase Family 31, in complex with Cyclophellitol Aziridine probe CF022

Summary for 5I23

Entry DOI	10.2210/pdb5i23/pdb
Descriptor	Oligosaccharide 4-alpha-D-glucosyltransferase, TETRAETHYLENE GLYCOL, SULFATE ION, ... (6 entities in total)
Functional Keywords	alpha glycosidase, cyclophellitol aziridine, inhibitor, probe, transferase
Biological source	Cellvibrio japonicus (strain Ueda107)
Total number of polymer chains	1
Total formula weight	95834.87
Authors	Wu, L.,Davies, G.J. (deposition date: 2016-02-08, release date: 2016-05-04, Last modification date: 2024-01-10)
Primary citation	Jiang, J.,Kuo, C.L.,Wu, L.,Franke, C.,Kallemeijn, W.W.,Florea, B.I.,van Meel, E.,van der Marel, G.A.,Codee, J.D.,Boot, R.G.,Davies, G.J.,Overkleeft, H.S.,Aerts, J.M. Detection of Active Mammalian GH31 alpha-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes. Acs Cent.Sci., 2:351-358, 2016 Cited by PubMed: 27280170 DOI: 10.1021/acscentsci.6b00057 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation