2H8R
 
 | | Hepatocyte Nuclear Factor 1b bound to DNA: MODY5 Gene Product | | 分子名称: | 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*G)-3', 5'-D(*GP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3', Hepatocyte nuclear factor 1-beta | | 著者 | Lu, P, Rha, G.B, Chi, Y.I. | | 登録日 | 2006-06-07 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta.
Biochemistry, 46, 2007
|
|
4LIP
 | |
3UXG
 | | Crystal structure of RFXANK | | 分子名称: | DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION | | 著者 | Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2011-12-05 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
|
|
3UR5
 | | Crystal Structure of PTE mutant K185R/I274N | | 分子名称: | COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, Parathion hydrolase | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-21 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
3URQ
 | | Crystal Structure of PTE mutant H254G/H257W/L303T/M317L/I106C/F132I/L271I/K185R/I274N/A80V/R67H with cyclohexyl methylphosphonate inhibitor | | 分子名称: | COBALT (II) ION, IMIDAZOLE, Parathion hydrolase, ... | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-22 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
3UR2
 | | Crystal Structure of PTE mutant H254G/H257W/L303T/K185R/I274N/A80V | | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, IMIDAZOLE, ... | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-21 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
3UPM
 | | Crystal Structure of PTE mutant H254Q/H257F/K185R/I274N | | 分子名称: | COBALT (II) ION, Parathion hydrolase | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-18 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
3URB
 | | Crystal Structure of PTE mutant H254G/H257W/L303T/M317L/I106C/F132I/L271I/K185R/I274N/A80V/R67H | | 分子名称: | COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, IMIDAZOLE, ... | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-21 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
3URA
 | | Crystal Structure of PTE mutant H254G/H257W/L303T/K185R/I274N/A80V/S61T | | 分子名称: | COBALT (II) ION, IMIDAZOLE, Parathion hydrolase | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-21 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
3URN
 | | Crystal Structure of PTE mutant H254G/H257W/L303T/K185R/I274N/A80V/S61T with cyclohexyl methylphosphonate inhibitor | | 分子名称: | COBALT (II) ION, IMIDAZOLE, Parathion hydrolase, ... | | 著者 | Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. | | 登録日 | 2011-11-22 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
Biochemistry, 51, 2012
|
|
7WMD
 | |
7WMK
 | | PQQ-dependent alcohol dehydrogenase complexed with PQQ | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ... | | 著者 | Chen, M, Yang, H, Lv, F. | | 登録日 | 2022-01-15 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structure-Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification.
J.Agric.Food Chem., 70, 2022
|
|
7VYX
 | | Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex | | 分子名称: | Non-target DNA strand, Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, Target DNA strand, ... | | 著者 | Zhang, B, Lin, J.Y, Perculija, V, OuYang, S.Y. | | 登録日 | 2021-11-15 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system
Nucleic Acids Res., 50, 2022
|
|
7XMV
 | | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P | | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | | 登録日 | 2022-04-27 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
|
|
7XN3
 | | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi | | 分子名称: | PHOSPHATE ION, Ribose-phosphate pyrophosphokinase | | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | | 登録日 | 2022-04-27 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
|
|
7XMU
 | | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P | | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | | 登録日 | 2022-04-26 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
|
|
7X6T
 | | Discovery of Selective BRD4 BD1 Inhibitor Based on [1,2,4] triazolo [4,3-b] pyridazine Scaffold | | 分子名称: | (2~{R})-2-[[3-methyl-6-(2-phenoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]amino]propanamide, Isoform C of Bromodomain-containing protein 4 | | 著者 | Cao, D, Xiong, B. | | 登録日 | 2022-03-08 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Discovery of Selective BRD4 BD1 Inhibitor Based on [1,2,4] triazolo [4,3-b] pyridazine Scaffold
To Be Published
|
|
7Y09
 | | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | | 著者 | Shen, H, Ji, C, Xiao, J. | | 登録日 | 2022-06-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
|
|
7YG2
 | | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DBLMSP2, ... | | 著者 | Shen, H, Ji, C, Xiao, J. | | 登録日 | 2022-07-09 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
|
|
7Y0J
 | |
7Y0H
 | |
7YHN
 | | ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X. | | 登録日 | 2022-07-14 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
J.Med.Chem., 65, 2022
|
|
7ZE0
 | | Solution structure of the PulM C-terminal domain from Klebsiella oxytoca | | 分子名称: | Type II secretion system protein M | | 著者 | Lopez-Castilla, A, Bardiaux, B, Nilges, M, Francetic, O, Izadi-Pruneyre, N. | | 登録日 | 2022-03-30 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Structure, 31, 2023
|
|
5ZKA
 | | Crystal structure of N-acetylneuraminate lyase from Fusobacterium nucleatum complexed with Pyruvate | | 分子名称: | 1,2-ETHANEDIOL, N-acetylneuraminate lyase, TRIETHYLENE GLYCOL | | 著者 | Kumar, J.P, Rao, H, Nayak, V, Ramaswamy, S. | | 登録日 | 2018-03-23 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum
Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
7DDE
 | | Cryo-EM structure of the Ape4 and Nbr1 complex | | 分子名称: | Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | | 著者 | Zhang, J, Ye, K. | | 登録日 | 2020-10-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
|
|
