7XMU

E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P

Summary for 7XMU

Entry DOI	10.2210/pdb7xmu/pdb
EMDB information	33305
Descriptor	Ribose-phosphate pyrophosphokinase, 5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	allosteric enzyme, kinase, transferase, nucleotide biosynthesis, atp-binding, magnesium, manganese, metal-binding, nucleotide-binding, biosynthetic protein
Biological source	Escherichia coli str. K-12 substr. MG1655
Total number of polymer chains	6
Total formula weight	217873.10
Authors	Hu, H.H.,Lu, G.M.,Chang, C.C.,Liu, J.L. (deposition date: 2022-04-26, release date: 2022-06-29, Last modification date: 2022-07-06)
Primary citation	Hu, H.H.,Lu, G.M.,Chang, C.C.,Li, Y.,Zhong, J.,Guo, C.J.,Zhou, X.,Yin, B.,Zhang, T.,Liu, J.L. Filamentation modulates allosteric regulation of PRPS. Elife, 11:-, 2022 Cited by PubMed: 35736577 DOI: 10.7554/eLife.79552 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.3 Å)

Structure validation