7XMU

E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, D, B, E, F...)	Ribose-phosphate pyrophosphokinase	polymer	321	35084.1	6	UniProt (P0A717) Pfam (PF13793) Pfam (PF14572)	Escherichia coli str. K-12 substr. MG1655	RPPK,5-phospho-D-ribosyl alpha-1-diphosphate,Phosphoribosyl diphosphate synthase,Phosphoribosyl pyrophosphate synthase,P-Rib-PP synthase,PRPP synthase,PRPPase
2	FA, G, KA, N, T... (F, A, C, D, B...)	5-O-phosphono-alpha-D-ribofuranose	non-polymer		230.1	6	Chemie (HSX)
3	AA, CA, GA, H, IA... (E, F, A, C, D...)	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
4	BA, HA, I, MA, P... (E, F, A, C, D...)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
5	DA, EA, JA, K, L... (E, F, A, C, D...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	12	Chemie (ADP)
6	QA, RA, SA, TA, UA... (A, D, B, E, F...)	water	water		18.0	822	Chemie (HOH)

Sequence modifications

A, D, B, E, F, C: 1 - 315 (UniProt: P0A717)

PDB	External Database	Details
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	210504.5
Non-Polymers*	Number of molecules	36
	Total formula weight	7368.6
All*	Total formula weight	217873.1

*Water molecules are not included.