7AZ7
 
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 37 bound | | 分子名称: | Beta sliding clamp, FORMIC ACID, PENTAETHYLENE GLYCOL, ... | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
7AZ6
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 36 bound | | 分子名称: | ACETATE ION, Beta sliding clamp, CHLORIDE ION, ... | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
7AZ8
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound | | 分子名称: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
7AZD
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 20 bound | | 分子名称: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
7AZK
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 35 bound | | 分子名称: | Beta sliding clamp, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | 登録日 | 2020-11-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
4V5T
 | | X-ray structure of the Grapevine Fanleaf virus | | 分子名称: | COAT PROTEIN | | 著者 | Schellenberger, P, Sauter, C, Lorber, B, Bron, P, Trapani, S, Bergdoll, M, Marmonier, A, Schmitt-Keichinger, C, Lemaire, O, Demangeat, G, Ritzenthaler, C. | | 登録日 | 2011-02-01 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights Into Viral Determinants of Nematode Mediated Grapevine Fanleaf Virus Transmission.
Plos Pathog., 7, 2011
|
|
3CL3
 | | Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome | | 分子名称: | NF-kappa-B essential modulator, ORF K13 | | 著者 | Bagneris, C, Ageichik, A.V, Cronin, N, Boshoff, C, Waksman, G, Barrett, T. | | 登録日 | 2008-03-18 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.
Mol.Cell, 30, 2008
|
|
3M1J
 | |
2BMC
 | | Aurora-2 T287D T288D complexed with PHA-680632 | | 分子名称: | (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE, SERINE THREONINE-PROTEIN KINASE 6 | | 著者 | Cameron, A.D, Izzo, G, Sagliano, A, Rusconi, L, Storici, P, Fancelli, D, Berta, D, Bindi, S, Catana, C, Forte, B, Giordano, P, Mantegani, S, Meroni, M, Moll, J, Pittala, V, Severino, D, Tonani, R, Varasi, M, Vulpetti, A, Vianello, P. | | 登録日 | 2005-03-11 | | 公開日 | 2005-03-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
J.Med.Chem., 48, 2005
|
|
5ZC3
 | |
3D21
 | | Crystal structure of a poplar wild-type thioredoxin h, PtTrxh4 | | 分子名称: | Thioredoxin H-type | | 著者 | Koh, C.S, Didierjean, C, Corbier, C, Rouhier, N, Jacquot, J.P, Gelhaye, E. | | 登録日 | 2008-05-07 | | 公開日 | 2008-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | An Atypical Catalytic Mechanism Involving Three Cysteines of Thioredoxin.
J.Biol.Chem., 283, 2008
|
|
3MR6
 | | Human DNA polymerase eta - DNA ternary complex with a CPD 2bp upstream of the active site (TT4) | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*C*AP*TP*CP*AP*(TTD)P*AP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*TP*CP*TP*CP*GP*TP*AP*AP*T)-3'), ... | | 著者 | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | | 登録日 | 2010-04-28 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
|
|
1ITM
 | | ANALYSIS OF THE SOLUTION STRUCTURE OF HUMAN INTERLEUKIN 4 DETERMINED BY HETERONUCLEAR THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE TECHNIQUES | | 分子名称: | INTERLEUKIN-4 | | 著者 | Redfield, C, Smith, L.J, Boyd, J, Lawrence, G.M.P, Edwards, R.G, Gershater, C.J, Smith, R.A.G, Dobson, C.M. | | 登録日 | 1994-02-28 | | 公開日 | 1994-05-31 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Analysis of the solution structure of human interleukin-4 determined by heteronuclear three-dimensional nuclear magnetic resonance techniques.
J.Mol.Biol., 238, 1994
|
|
1IRA
 | | COMPLEX OF THE INTERLEUKIN-1 RECEPTOR WITH THE INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL1RA) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-1 RECEPTOR, INTERLEUKIN-1 RECEPTOR ANTAGONIST | | 著者 | Schreuder, H.A, Tardif, C, Tramp-Kalmeyer, S, Soffientini, A, Sarubbi, E, Akeson, A, Bowlin, T, Yanofsky, S, Barrett, R.W. | | 登録日 | 1998-04-09 | | 公開日 | 1998-06-17 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.
Nature, 386, 1997
|
|
8GXP
 | | Complex structure of RORgama with betulinic acid | | 分子名称: | Betulinic acid, Nuclear receptor ROR-gamma | | 著者 | Zhang, X.L, Xu, C, Bai, F. | | 登録日 | 2022-09-20 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists.
Eur.J.Med.Chem., 257, 2023
|
|
2BWR
 | | Crystal Structure of Psathyrella Velutina Lectin at 1.5A Resolution | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Cioci, G, Mitchell, E.P, Chazalet, V, Gautier, C, Oscarson, S, Debray, H, Perez, S, Imberty, A. | | 登録日 | 2005-07-18 | | 公開日 | 2006-01-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Beta-Propeller Crystal Structure of Psathyrella Velutina Lectin: An Integrin-Like Fungal Protein Interacting with Monosaccharides and Calcium.
J.Mol.Biol., 357, 2006
|
|
5ZWV
 | | Structural Basis for the Enantioselectivity of Est-Y29 toward (S)-ketoprofen | | 分子名称: | Est-Y29 | | 著者 | Ngo, D.T, Oh, C, Park, K, Nguyen, L, Byun, H.M, Kim, S, Yoon, S, Ryu, Y, Ryu, B.H, Kim, T.D, Yang, J.W. | | 登録日 | 2018-05-17 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural Basis for the Enantioselectivity of Esterase Est-Y29 toward (S)-Ketoprofen
Acs Catalysis, 9, 2019
|
|
3MR2
 | | Human DNA polymerase eta in complex with normal DNA and incoming nucleotide (Nrm) | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*T*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | | 登録日 | 2010-04-28 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
|
|
3DOB
 | | Peptide-binding domain of Heat shock 70 kDa protein F44E5.5 from C.elegans. | | 分子名称: | BETA-MERCAPTOETHANOL, Heat shock 70 kDa protein F44E5.5 | | 著者 | Osipiuk, J, Hatzos, C, Gu, M, Zhang, R, Voisine, C, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-07-03 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | X-ray crystal structure of Peptide-binding domain of Heat shock 70 kDa protein F44E5.5 from C.elegans.
To be Published
|
|
5ZVV
 | | Structure of SeMet-phAimR | | 分子名称: | AimR transcriptional regulator, GLYCEROL | | 著者 | Cheng, W, Dou, C. | | 登録日 | 2018-05-13 | | 公開日 | 2018-09-05 | | 最終更新日 | 2019-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities.
Nat Microbiol, 3, 2018
|
|
8HAY
 | | d4-bound btDPP4 | | 分子名称: | (1~{R})-1-[[4-[5-[[(1~{R})-6,7-dimethoxy-2-methyl-3,4-dihydro-1~{H}-isoquinolin-1-yl]methyl]-2-methoxy-phenoxy]phenyl]methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1~{H}-isoquinoline, btDPP4 | | 著者 | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | | 登録日 | 2022-10-27 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target.
Science, 381, 2023
|
|
3D9H
 | | Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein | | 分子名称: | cDNA FLJ77766, highly similar to Homo sapiens ankyrin repeat and SOCS box-containing 9 (ASB9), transcript variant 2, ... | | 著者 | Fei, X, Gu, X, Fan, S, Zhang, C, Ji, C. | | 登録日 | 2008-05-27 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
To be published
|
|
6A6B
 | | cryo-em structure of alpha-synuclein fiber | | 分子名称: | Alpha-synuclein | | 著者 | Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X. | | 登録日 | 2018-06-27 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy
Cell Res., 28, 2018
|
|
5ZW6
 | | Structure of spAimR | | 分子名称: | AimR transcriptional regulator, GLY-MET-PRO-ARG-GLY-ALA | | 著者 | Cheng, W, Dou, C. | | 登録日 | 2018-05-14 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities.
Nat Microbiol, 3, 2018
|
|
4B4Y
 | | crystal structure of the neuroglobin from the photosymbiotic marine acoel Symsagittifera roscoffensis | | 分子名称: | NEUROGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lechauve, C, Jager, M, Laguerre, L, Kiger, L, Correc, G, Leroux, C, Vinogradov, S, Czjzek, M, Marden, M.C, Bailly, X. | | 登録日 | 2012-08-01 | | 公開日 | 2013-01-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Neuroglobins: Pivotal Proteins Associated with Emerging Neural Systems and Precursors of Metazoan Globin Diversity.
J.Biol.Chem., 288, 2013
|
|
