3S9D

binary complex between IFNa2 and IFNAR2

Summary for 3S9D

Entry DOI	10.2210/pdb3s9d/pdb
Related	3S8W 3S98
Descriptor	Interferon alpha-2, Interferon alpha/beta receptor 2, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	human, type i interferons, ifna2, ifnar2, sub-complex of the interferon signaling complex, signaling protein-receptor complex, signaling protein/receptor
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P01563 Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P48551
Total number of polymer chains	4
Total formula weight	84417.90
Authors	Thomas, C.,Garcia, K.C. (deposition date: 2011-06-01, release date: 2011-08-31, Last modification date: 2023-09-13)
Primary citation	Thomas, C.,Moraga, I.,Levin, D.,Krutzik, P.O.,Podoplelova, Y.,Trejo, A.,Lee, C.,Yarden, G.,Vleck, S.E.,Glenn, J.S.,Nolan, G.P.,Piehler, J.,Schreiber, G.,Garcia, K.C. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell(Cambridge,Mass.), 146:621-632, 2011 Cited by PubMed: 21854986 DOI: 10.1016/j.cell.2011.06.048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9999 Å)

Structure validation