2VAN

Nucleotidyl Transfer Mechanism of Mismatched dNTP Incorporation by DNA Polymerase b by Structural and Kinetic Analyses

Summary for 2VAN

Entry DOI	10.2210/pdb2van/pdb
Related	1BNO 1BNP 1BPB 1BPD 1BPE 1DK2 1DK3 1HUO 1HUZ 1JN3 1NOM 1RPL 1ZQU 1ZQV 1ZQW 1ZQX 1ZQY 1ZQZ 2BPC 2BPF 2BPG
Descriptor	DNA POLYMERSE BETA (2 entities in total)
Functional Keywords	nucleotidyltransferase, dna-directed dna polymerase, lyase, nucleus, dna damage, dna synthesis, dna replication, dna repair, transferase, dna-binding, metal-binding
Biological source	RATTUS NORVEGICUS (NORWAY RAT)
Cellular location	Nucleus: P06766
Total number of polymer chains	1
Total formula weight	28391.02
Authors	Chan, H.,Chou, C.,Tang, K.,Niebuhr, M.,Tung, C.,Tsai, M. (deposition date: 2007-09-03, release date: 2008-04-15, Last modification date: 2023-12-13)
Primary citation	Tang, K.,Niebuhr, M.,Tung, C.,Chan, H.,Chou, C.,Tsai, M. Mismatched Dntp Incorporation by DNA Polymerase Beta Does not Proceed Via Globally Different Conformational Pathways. Nucleic Acids Res., 36:2948-, 2008 Cited by PubMed: 18385153 DOI: 10.1093/NAR/GKN138 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation