6GSN
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6GSM
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![BU of 6gsm by Molmil](/molmil-images/mine/6gsm) | Structure of a partial yeast 48S preinitiation complex in open conformation. | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-06-14 | Release date: | 2019-07-31 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (5.15 Å) | Cite: | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection. Nucleic Acids Res., 2021
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6FYX
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![BU of 6fyx by Molmil](/molmil-images/mine/6fyx) | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-03-12 | Release date: | 2018-12-05 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
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6FYY
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![BU of 6fyy by Molmil](/molmil-images/mine/6fyy) | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-03-12 | Release date: | 2018-12-05 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
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2V5H
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![BU of 2v5h by Molmil](/molmil-images/mine/2v5h) | Controlling the storage of nitrogen as arginine: the complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC 7942 | Descriptor: | ACETYLGLUTAMATE KINASE, CHLORIDE ION, GLYCEROL, ... | Authors: | Llacer, J.L, Marco-Marin, C, Gil-Ortiz, F, Fita, I, Rubio, V. | Deposit date: | 2007-07-04 | Release date: | 2007-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine. Proc.Natl.Acad.Sci.USA, 104, 2007
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3JAP
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![BU of 3jap by Molmil](/molmil-images/mine/3jap) | Structure of a partial yeast 48S preinitiation complex in closed conformation | Descriptor: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | Deposit date: | 2015-06-18 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex. Mol.Cell, 59, 2015
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3JAM
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![BU of 3jam by Molmil](/molmil-images/mine/3jam) | CryoEM structure of 40S-eIF1A-eIF1 complex from yeast | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | Deposit date: | 2015-06-17 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex. Mol.Cell, 59, 2015
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2XKP
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2XHK
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2XG8
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2XKO
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2XGX
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![BU of 2xgx by Molmil](/molmil-images/mine/2xgx) | Crystal structure of transcription factor NtcA from Synechococcus elongatus (mercury derivative) | Descriptor: | 2-OXOGLUTARIC ACID, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLOBAL NITROGEN REGULATOR, ... | Authors: | Llacer, J.L, Castells, M.A, Rubio, V. | Deposit date: | 2010-06-08 | Release date: | 2010-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii. Proc.Natl.Acad.Sci.USA, 107, 2010
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2JJ4
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![BU of 2jj4 by Molmil](/molmil-images/mine/2jj4) | The complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC7942 | Descriptor: | ACETYLGLUTAMATE KINASE, N-ACETYL-L-GLUTAMATE, NITROGEN REGULATORY PROTEIN P-II | Authors: | Llacer, J.L, Marco-Marin, C, Gil-Ortiz, F, Fita, I, Rubio, V. | Deposit date: | 2007-07-04 | Release date: | 2007-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine Proc.Natl.Acad.Sci.USA, 104, 2007
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2JER
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6QG1
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![BU of 6qg1 by Molmil](/molmil-images/mine/6qg1) | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG2
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![BU of 6qg2 by Molmil](/molmil-images/mine/6qg2) | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG6
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![BU of 6qg6 by Molmil](/molmil-images/mine/6qg6) | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.65 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG0
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![BU of 6qg0 by Molmil](/molmil-images/mine/6qg0) | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG5
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![BU of 6qg5 by Molmil](/molmil-images/mine/6qg5) | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (10.1 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG3
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![BU of 6qg3 by Molmil](/molmil-images/mine/6qg3) | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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8P9Y
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![BU of 8p9y by Molmil](/molmil-images/mine/8p9y) | SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | Authors: | Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L. | Deposit date: | 2023-06-06 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein. J.Med.Chem., 66, 2023
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8P99
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![BU of 8p99 by Molmil](/molmil-images/mine/8p99) | SARS-CoV-2 S-protein:D614G mutant in 1-up conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1,Spike glycoprotein | Authors: | Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L. | Deposit date: | 2023-06-05 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein. J.Med.Chem., 66, 2023
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5LMQ
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![BU of 5lmq by Molmil](/molmil-images/mine/5lmq) | Structure of bacterial 30S-IF1-IF3-mRNA-tRNA translation pre-initiation complex, open form (state-2A) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2016-08-01 | Release date: | 2016-10-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
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5LMO
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![BU of 5lmo by Molmil](/molmil-images/mine/5lmo) | Structure of bacterial 30S-IF1-IF3-mRNA translation pre-initiation complex (state-1B) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2016-08-01 | Release date: | 2016-10-05 | Last modified: | 2019-10-02 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
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5LMV
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![BU of 5lmv by Molmil](/molmil-images/mine/5lmv) | Structure of bacterial 30S-IF1-IF2-IF3-mRNA-tRNA translation pre-initiation complex(state-III) | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2016-08-01 | Release date: | 2016-10-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
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