4NUG
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4R26
| Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | Descriptor: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | Authors: | Garces, F, Kong, L, Wilson, I.A. | Deposit date: | 2014-08-08 | Release date: | 2014-10-08 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (2.4969 Å) | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
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4R2G
| Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Garces, F, Wilson, I.A. | Deposit date: | 2014-08-11 | Release date: | 2014-10-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.283 Å) | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
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3IDM
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3IDI
| Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide ALDKWNQ | Descriptor: | 2F5 Fab heavy chain, 2F5 Fab light chain, GLYCEROL, ... | Authors: | Julien, J.-P, Bryson, S, Pai, E.F. | Deposit date: | 2009-07-21 | Release date: | 2010-03-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83, 2009
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3IDJ
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3IDN
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5UY3
| Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody | Descriptor: | Antibody PGT144 Fab heavy chain, Antibody PGT144 Fab light chain | Authors: | Julien, J.-P, Lee, J.H, Wilson, I.A. | Deposit date: | 2017-02-23 | Release date: | 2017-04-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure. Immunity, 46, 2017
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4JPI
| Crystal structure of a putative VRC01 germline precursor Fab | Descriptor: | GLYCEROL, Putative VRC01 germline Fab heavy chain, Putative VRC01 germline Fab light chain | Authors: | Julien, J.-P, Diwanji, D.C, Jardine, J, Schief, W.R, Wilson, I.A. | Deposit date: | 2013-03-19 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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4LG2
| Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA | Descriptor: | Polymerase cofactor, dsRNA | Authors: | Bale, S, Julien, J.-P, Bornholdt, Z.A, Krois, A.S, Wilson, I.A, Saphire, E.O. | Deposit date: | 2013-06-27 | Release date: | 2013-07-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism. J.Virol., 87, 2013
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4JPK
| Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6, ... | Authors: | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | Deposit date: | 2013-03-19 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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4JPJ
| Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | Authors: | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | Deposit date: | 2013-03-19 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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4JM4
| Crystal Structure of PGT 135 Fab | Descriptor: | PGT 135 Heavy Chain, PGT 135 Light Chain | Authors: | Kong, L, Wilson, I.A. | Deposit date: | 2013-03-13 | Release date: | 2013-05-29 | Last modified: | 2013-07-17 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat.Struct.Mol.Biol., 20, 2013
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4JM2
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3Q1S
| HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ... | Authors: | Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A. | Deposit date: | 2010-12-17 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope. J.Mol.Biol., 414, 2011
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3U1S
| Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody | Descriptor: | Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ... | Authors: | Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A. | Deposit date: | 2011-09-30 | Release date: | 2011-12-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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3TV3
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3TWC
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3TYG
| Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3) | Descriptor: | Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ... | Authors: | Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2011-09-25 | Release date: | 2011-10-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science, 334, 2011
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6AND
| Pinatuzumab Fab in complex with anti-Kappa VHH domain | Descriptor: | Anti-kappa VHH domain, GLYCEROL, Pinatuzumab Fab Heavy chain, ... | Authors: | Ereno-Orbea, J, Sicard, T, Julien, J.-P. | Deposit date: | 2017-08-12 | Release date: | 2018-01-31 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J. Mol. Biol., 430, 2018
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5IF0
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6ANI
| Coltuximab Fab in complex with anti-Kappa VHH domain | Descriptor: | Anti-Kappa VHH domain, Coltuximab Fab heavy chain, Coltuximab Fab light chain, ... | Authors: | Ereno Orbea, J, Sicard, T, Julien, J.-P. | Deposit date: | 2017-08-13 | Release date: | 2018-01-31 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J. Mol. Biol., 430, 2018
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5IES
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6ANA
| LL2 Fab in complex with anti-Kappa VHH domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, LL2 Fab Heavy Chain, LL2 Fab Light Chain, ... | Authors: | Sicard, T, Ereno Orbea, J, Julien, J.-P. | Deposit date: | 2017-08-12 | Release date: | 2018-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J. Mol. Biol., 430, 2018
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5IFA
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