3IDM

Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide analog ELD(Nrg)WAS

Summary for 3IDM

Entry DOI	10.2210/pdb3idm/pdb
Related	2P8M 3D0L 3IDG 3IDI 3IDJ 3IDN
Descriptor	2F5 Fab light chain, 2F5 Fab heavy chain, gp41 MPER peptide analog, ... (4 entities in total)
Functional Keywords	hiv-1, gp41, mper, 2f5, immune system
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	49530.47
Authors	Julien, J.-P.,Bryson, S.,Pai, E.F. (deposition date: 2009-07-21, release date: 2010-02-02, Last modification date: 2023-11-15)
Primary citation	Bryson, S.,Julien, J.P.,Hynes, R.C.,Pai, E.F. Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83:11862-11875, 2009 Cited by PubMed: 19740978 DOI: 10.1128/JVI.01604-09 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.24 Å)

Structure validation