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8K3C
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BU of 8k3c by Molmil
Nipah virus Attachment glycoprotein with 41-6 antibody fragment
Descriptor: Glycoprotein G, Heavy chain of 41-6 Fab fragments, Light chain of 41-6 Fab fragment
Authors:Sun, M.M.
Deposit date:2023-07-15
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Potent human neutralizing antibodies against Nipah virus derived from two ancestral antibody heavy chains.
Nat Commun, 15, 2024
2MVW
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BU of 2mvw by Molmil
Solution structure of the TRIM19 B-box1 (B1) of human promyelocytic leukemia (PML)
Descriptor: Protein PML, ZINC ION
Authors:Huang, S, Naik, M.T, Fan, P, Wang, Y, Chang, C, Huang, T.
Deposit date:2014-10-17
Release date:2014-11-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The B-box 1 dimer of human promyelocytic leukemia protein.
J.Biomol.Nmr, 60, 2014
7C2L
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BU of 7c2l by Molmil
S protein of SARS-CoV-2 in complex bound with 4A8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R.H, Zhang, Y.Y, Guo, Y.Y, Li, Y.N, Xia, L, Zhou, Q.
Deposit date:2020-05-08
Release date:2020-07-01
Last modified:2021-02-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2.
Science, 369, 2020
7AEP
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BU of 7aep by Molmil
Solution structure of U1-A RRM2 (190-282)
Descriptor: U1 small nuclear ribonucleoprotein A
Authors:Campagne, S, Allain, F.H.
Deposit date:2020-09-18
Release date:2021-02-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands.
Nucleic Acids Res., 49, 2021
5IAO
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BU of 5iao by Molmil
Structure and mapping of spontaneous mutational sites of PyrR from Mycobacterium tuberculosis
Descriptor: 5-FLUOROURACIL, Bifunctional protein PyrR
Authors:Sivaraman, J, Ghode, P, Ramachandran, S.
Deposit date:2016-02-21
Release date:2016-03-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Structure and mapping of spontaneous mutational sites of PyrR from Mycobacterium tuberculosis
Biochem.Biophys.Res.Commun., 471, 2016
3QPL
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BU of 3qpl by Molmil
G106W mutant of EthR from Mycobacterium tuberculosis
Descriptor: HTH-type transcriptional regulator EthR
Authors:Carette, X, Willery, E, Hoos, S, Lecat-Guillet, N, Frenois, F, Dirie, B, Villeret, V, England, P, Deprez, B, Locht, C, Willand, N, Baulard, A.
Deposit date:2011-02-14
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic Acids Res., 40, 2012
5M3J
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BU of 5m3j by Molmil
Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD
Descriptor: DNA-directed RNA polymerase subunit, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Lukarska, M, Pflug, A, Cusack, S.
Deposit date:2016-10-14
Release date:2016-12-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
5M3H
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BU of 5m3h by Molmil
Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD
Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Lukarska, M, Pflug, A, Cusack, S.
Deposit date:2016-10-14
Release date:2016-12-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
6EVJ
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BU of 6evj by Molmil
Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primer
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(GDM))-R(P*AP*AP*U)-3'), ...
Authors:Pflug, A, Cusack, S.
Deposit date:2017-11-01
Release date:2017-12-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUX
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BU of 6eux by Molmil
Structure of the midlink and cap-binding domains of influenza B polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUV
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BU of 6euv by Molmil
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)
Descriptor: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, NICKEL (II) ION, Polymerase basic protein 2
Authors:Cusack, S, Lethier, M.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUY
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BU of 6euy by Molmil
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2, SULFATE ION
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUW
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BU of 6euw by Molmil
Crystal structure of the cap-binding domain of the PB2 subunit of influenza A/H5N1 polymerase bound to an azaindazole inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, GLYCEROL, Polymerase basic protein 2
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EVK
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BU of 6evk by Molmil
Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue m7GTP
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, Polymerase acidic protein, ...
Authors:Pflug, A, Cusack, S.
Deposit date:2017-11-01
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6ZWJ
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BU of 6zwj by Molmil
Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution
Descriptor: CITRIC ACID, GLYCEROL, Transaldolase
Authors:Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K.
Deposit date:2020-07-28
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWF
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BU of 6zwf by Molmil
Neisseria gonorrhoeae transaldolase
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ...
Authors:Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
Deposit date:2020-07-28
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWH
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BU of 6zwh by Molmil
Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
Authors:Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
Deposit date:2020-07-28
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZX4
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BU of 6zx4 by Molmil
Neisseria gonorrhoeae transaldolase
Descriptor: CITRIC ACID, GLYCEROL, Transaldolase
Authors:Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
Deposit date:2020-07-29
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7B0L
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BU of 7b0l by Molmil
Neisseria gonorrhoeae transaldolase, low-dose inhouse
Descriptor: CITRIC ACID, Transaldolase
Authors:Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
Deposit date:2020-11-20
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
2JTA
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BU of 2jta by Molmil
NMR structure of immunosuppressory ubiquitin fragment is similar to related ubiquitin region.
Descriptor: 10-mer ubiquitin peptide
Authors:Jaremko, M, Jaremko, L, Zhukov, I, Cebrat, M.
Deposit date:2007-07-21
Release date:2008-07-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The immunosuppressive activity and solution structures of ubiquitin fragments.
Biopolymers, 91, 2009
7VIC
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BU of 7vic by Molmil
The crystal structure of SARS-CoV-2 3C-like protease in complex with a traditional Chinese Medicine Inhibitors
Descriptor: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, 3C-like proteinase
Authors:Zhong, B, Chen, B, Zhou, H, Sun, L.
Deposit date:2021-09-26
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Oridonin Inhibits SARS-CoV-2 by Targeting Its 3C-Like Protease.
Small Sci, 2, 2022
3SZX
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BU of 3szx by Molmil
Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Descriptor: RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
Authors:Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
Deposit date:2011-07-19
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
3SYW
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BU of 3syw by Molmil
Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Descriptor: PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
Authors:Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
Deposit date:2011-07-18
Release date:2012-04-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
3SJ2
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BU of 3sj2 by Molmil
A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome
Descriptor: ACETATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3')
Authors:Kumar, A, Pengfei, F, Park, H, Nettles, K, Guo, M, Disney, M.D.
Deposit date:2011-06-20
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome.
Chembiochem, 12, 2011
5BTM
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BU of 5btm by Molmil
Crystal structure of AUUCU repeating RNA that causes spinocerebellar ataxia type 10 (SCA10)
Descriptor: MAGNESIUM ION, RNA (55-mer), SODIUM ION
Authors:Park, H.
Deposit date:2015-06-03
Release date:2015-07-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.778 Å)
Cite:Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10).
Biochemistry, 54, 2015

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