8K3C

Nipah virus Attachment glycoprotein with 41-6 antibody fragment

Summary for 8K3C

Entry DOI	10.2210/pdb8k3c/pdb
EMDB information	36849
Descriptor	Light chain of 41-6 Fab fragment, Heavy chain of 41-6 Fab fragments, Glycoprotein G (3 entities in total)
Functional Keywords	nipah virus, attachment glycoprotein, tetramer complex, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	154038.86
Authors	Sun, M.M. (deposition date: 2023-07-15, release date: 2024-05-01)
Primary citation	Chen, L.,Sun, M.,Zhang, H.,Zhang, X.,Yao, Y.,Li, M.,Li, K.,Fan, P.,Zhang, H.,Qin, Y.,Zhang, Z.,Li, E.,Chen, Z.,Guan, W.,Li, S.,Yu, C.,Zhang, K.,Gong, R.,Chiu, S. Potent human neutralizing antibodies against Nipah virus derived from two ancestral antibody heavy chains. Nat Commun, 15:2987-2987, 2024 Cited by PubMed: 38582870 DOI: 10.1038/s41467-024-47213-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.88 Å)

Structure validation