6EVK

Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue m7GTP

Summary for 6EVK

Entry DOI	10.2210/pdb6evk/pdb
Descriptor	Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (9 entities in total)
Functional Keywords	influenza virus, rna-dependent rna polymerase, cap analogue, viral protein
Biological source	Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10)) More
Cellular location	Host nucleus : H6QM90
Total number of polymer chains	5
Total formula weight	277030.17
Authors	Pflug, A.,Cusack, S. (deposition date: 2017-11-01, release date: 2017-12-13, Last modification date: 2024-01-17)
Primary citation	Pflug, A.,Gaudon, S.,Resa-Infante, P.,Lethier, M.,Reich, S.,Schulze, W.M.,Cusack, S. Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46:956-971, 2018 Cited by PubMed: 29202182 DOI: 10.1093/nar/gkx1210 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation