7VIC
The crystal structure of SARS-CoV-2 3C-like protease in complex with a traditional Chinese Medicine Inhibitors
Summary for 7VIC
Entry DOI | 10.2210/pdb7vic/pdb |
Descriptor | 3C-like proteinase, (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one (3 entities in total) |
Functional Keywords | sars-cov-2, inhibitor, 3clpro, virus, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 1 |
Total formula weight | 34192.00 |
Authors | |
Primary citation | Zhong, B.,Peng, W.,Du, S.,Chen, B.,Feng, Y.,Hu, X.,Lai, Q.,Liu, S.,Zhou, Z.W.,Fang, P.,Wu, Y.,Gao, F.,Zhou, H.,Sun, L. Oridonin Inhibits SARS-CoV-2 by Targeting Its 3C-Like Protease. Small Sci, 2:2100124-2100124, 2022 Cited by PubMed: 35600064DOI: 10.1002/smsc.202100124 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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