Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD

Summary for 5M3H

DescriptorPolymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (9 entities in total)
Functional Keywordsinfluenza rna-dependent rna polymerase, vrna promoter, pol ii serine 5 phosphorylated ctd peptide, transferase
Biological sourceInfluenza A virus
Cellular locationHost cytoplasm . Host nucleus  H6QM92
Host nucleus  H6QM90
Total number of polymer chains7
Total molecular weight281102.49
Lukarska, M.,Pflug, A.,Cusack, S. (deposition date: 2016-10-14, release date: 2016-12-21, Last modification date: 2017-12-27)
Primary citation
Lukarska, M.,Fournier, G.,Pflug, A.,Resa-Infante, P.,Reich, S.,Naffakh, N.,Cusack, S.
Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541:117-121, 2017
PubMed: 28002402 (PDB entries with the same primary citation)
DOI: 10.1038/nature20594
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.2462 0.8% 3.1% 11.5% 0.57MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-21