5M3H

Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polymerase acidic protein	polymer	728	84241.6	1	UniProt (H6QM92) Pfam (PF00603)	Influenza A virus
2	B (B)	RNA-directed RNA polymerase catalytic subunit	polymer	776	87936.3	1	UniProt (H6QM91) Pfam (PF00602)	Influenza A virus
3	C (C)	Polymerase basic protein 2	polymer	797	90168.3	1	UniProt (H6QM90) Pfam (PF20947) Pfam (PF20948) Pfam (PF20949) Pfam (PF20950) Pfam (PF00604) Pfam (PF20951) Pfam (PF20952)	Influenza A virus
4	D (R)	RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*U)-3')	polymer	18	5584.3	1		Influenza A virus
5	E (V)	RNA 5'-pAGUAGUAACAAGAGGG	polymer	16	5248.2	1		Influenza A virus
6	F, G (X, Y)	TYR-SER-PRO-THR-SEP-PRO	polymer	28	3216.9	2	Pfam (PF05001) UniProt (by SIFTS) (P24928)	Homo sapiens
7	H (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
8	I, J, K, L, M... (A, B, C)	PHOSPHATE ION	non-polymer		95.0	15	Chemie (PO4)
9	AA, BA, CA, X, Y... (R, V, X, A, B...)	water	water		18.0	250	Chemie (HOH)

Sequence modifications

A: 1 - 713 (UniProt: H6QM92)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Gly 714	-	expression tag
Ser 715	-	expression tag
Gly 716	-	expression tag
Ser 717	-	expression tag
Gly 718	-	expression tag
Glu 719	-	expression tag
Asn 720	-	expression tag
Leu 721	-	expression tag
Tyr 722	-	expression tag
Phe 723	-	expression tag
Gln 724	-	expression tag

B: 1 - 756 (UniProt: H6QM91)

PDB	External Database	Details
Gly -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Gly 757	-	expression tag
Ser 758	-	expression tag
Gly 759	-	expression tag
Ser 760	-	expression tag
Gly 761	-	expression tag
Glu 762	-	expression tag
Asn 763	-	expression tag
Leu 764	-	expression tag
Tyr 765	-	expression tag
Phe 766	-	expression tag
Gln 767	-	expression tag

C: 1 - 760 (UniProt: H6QM90)

PDB	External Database	Details
Gly -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Gly 761	-	expression tag
Trp 762	-	expression tag
Ser 763	-	expression tag
His 764	-	expression tag
Pro 765	-	expression tag
Gln 766	-	expression tag
Phe 767	-	expression tag
Glu 768	-	expression tag
Lys 769	-	expression tag
Gly 770	-	expression tag
Trp 771	-	expression tag
Ser 772	-	expression tag
His 773	-	expression tag
Pro 774	-	expression tag
Gln 775	-	expression tag
Phe 776	-	expression tag
Glu 777	-	expression tag
Lys 778	-	expression tag
Gly 779	-	expression tag
Ser 780	-	expression tag
Gly 781	-	expression tag
Ser 782	-	expression tag
Glu 783	-	expression tag
Asn 784	-	expression tag
Leu 785	-	expression tag
Tyr 786	-	expression tag
Phe 787	-	expression tag
Gln 788	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	279612.5
Non-Polymers*	Number of molecules	16
	Total formula weight	1490.0
All*	Total formula weight	281102.5

*Water molecules are not included.