8YRG
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![BU of 8yrg by Molmil](/molmil-images/mine/8yrg) | CryoEM structure of fospropofol-bound MRGPRX4-Gq complex | Descriptor: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Cao, C, Fay, J.F, Roth, B.L. | Deposit date: | 2024-03-21 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Sci Transl Med, 16, 2024
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6N2W
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![BU of 6n2w by Molmil](/molmil-images/mine/6n2w) | The structure of Stable-5-Lipoxygenase bound to NDGA | Descriptor: | 4-[(2R,3S)-3-[(3,4-DIHYDROXYPHENYL)METHYL]-2-METHYLBUTYL]BENZENE-1,2-DIOL, Arachidonate 5-lipoxygenase, FE (II) ION | Authors: | Newcomer, M.E, Gilbert, N.C, Neau, D.B. | Deposit date: | 2018-11-14 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nat.Chem.Biol., 16, 2020
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6NCF
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![BU of 6ncf by Molmil](/molmil-images/mine/6ncf) | The structure of Stable-5-Lipoxygenase bound to AKBA | Descriptor: | (3alpha,8alpha,17alpha,18alpha)-3-(acetyloxy)-11-oxours-12-en-23-oic acid, Arachidonate 5-lipoxygenase, FE (II) ION | Authors: | Newcomer, M.E, Gilbert, N.C, Neau, D.B. | Deposit date: | 2018-12-11 | Release date: | 2020-05-13 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (2.871 Å) | Cite: | Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nat.Chem.Biol., 16, 2020
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6NLE
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![BU of 6nle by Molmil](/molmil-images/mine/6nle) | X-ray structure of LeuT with V269 deletion | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Navratna, V, Yang, D, Gouaux, E. | Deposit date: | 2019-01-08 | Release date: | 2020-01-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.615 Å) | Cite: | Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion inSLC6A3. Proc.Natl.Acad.Sci.USA, 116, 2019
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5ZBH
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![BU of 5zbh by Molmil](/molmil-images/mine/5zbh) | The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885 | Descriptor: | Neuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1, dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate | Authors: | Yang, Z, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2018-02-11 | Release date: | 2018-04-25 | Last modified: | 2018-05-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of ligand binding modes at the neuropeptide Y Y1receptor Nature, 556, 2018
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5ZBQ
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![BU of 5zbq by Molmil](/molmil-images/mine/5zbq) | The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299 | Descriptor: | Neuropeptide Y receptor type 1,T4 Lysozyme, N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N'-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide | Authors: | Yang, Z, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2018-02-12 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of ligand binding modes at the neuropeptide Y Y1receptor Nature, 556, 2018
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6CHV
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![BU of 6chv by Molmil](/molmil-images/mine/6chv) | Proteus vulgaris HigA antitoxin bound to DNA | Descriptor: | Antitoxin HigA, MAGNESIUM ION, pHigCryst3, ... | Authors: | Schureck, M.A, Hoffer, E.D, Onuoha, N, Dunham, C.M. | Deposit date: | 2018-02-23 | Release date: | 2019-02-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of transcriptional regulation by the HigA antitoxin. Mol.Microbiol., 111, 2019
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6D0U
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6UBO
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![BU of 6ubo by Molmil](/molmil-images/mine/6ubo) | Fluorogen Activating Protein Dib1 | Descriptor: | 12-(diethylamino)-2,2-bis(fluoranyl)-4,5-dimethyl-5-aza-3-azonia-2-boranuidatricyclo[7.4.0.0^{3,7}]trideca-1(13),3,7,9,11-pentaen-6-one, CITRIC ACID, Outer membrane lipoprotein Blc, ... | Authors: | Muslinkina, L, Pletneva, N, Pletnev, V.Z, Pletnev, S. | Deposit date: | 2019-09-12 | Release date: | 2020-09-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structure-Based Rational Design of Two Enhanced Bacterial Lipocalin Blc Tags for Protein-PAINT Super-resolution Microscopy. Acs Chem.Biol., 15, 2020
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6CF1
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![BU of 6cf1 by Molmil](/molmil-images/mine/6cf1) | Proteus vulgaris HigA antitoxin structure | Descriptor: | Antitoxin HigA, POTASSIUM ION | Authors: | Schureck, M.A, Hoffer, E.D, Ei Cho, S, Dunham, C.M. | Deposit date: | 2018-02-13 | Release date: | 2019-02-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis of transcriptional regulation by the HigA antitoxin. Mol.Microbiol., 111, 2019
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3MF9
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![BU of 3mf9 by Molmil](/molmil-images/mine/3mf9) | Computationally designed endo-1,4-beta-xylanase | Descriptor: | Endo-1,4-beta-xylanase, SULFATE ION | Authors: | Morin, A, Harp, J.M. | Deposit date: | 2010-04-01 | Release date: | 2010-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Computational design of an endo-1,4-{beta}-xylanase ligand binding site. Protein Eng.Des.Sel., 24, 2011
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3MFC
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![BU of 3mfc by Molmil](/molmil-images/mine/3mfc) | Computationally designed end0-1,4-beta,xylanase | Descriptor: | Endo-1,4-beta-xylanase, SULFATE ION | Authors: | Morin, A, Harp, J.M. | Deposit date: | 2010-04-01 | Release date: | 2010-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Computational design of an endo-1,4-{beta}-xylanase ligand binding site. Protein Eng.Des.Sel., 24, 2011
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3MF6
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![BU of 3mf6 by Molmil](/molmil-images/mine/3mf6) | Computationally designed endo-1,4-beta-xylanase | Descriptor: | Endo-1,4-beta-xylanase, SULFATE ION | Authors: | Morin, A, Harp, J.M. | Deposit date: | 2010-04-01 | Release date: | 2010-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Computational design of an endo-1,4-{beta}-xylanase ligand binding site. Protein Eng.Des.Sel., 24, 2011
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5UWV
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![BU of 5uwv by Molmil](/molmil-images/mine/5uwv) | Crystal structure of Mycobacterium abscessus L,D-transpeptidase 2 | Descriptor: | L,D-TRANSPEPTIDASE 2 | Authors: | Kumar, P, Ginell, S.L, Lamichhane, G. | Deposit date: | 2017-02-21 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins. Antimicrob. Agents Chemother., 61, 2017
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4HFW
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![BU of 4hfw by Molmil](/molmil-images/mine/4hfw) | Anti Rotavirus Antibody | Descriptor: | 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION | Authors: | Spiller, B.W, Aiyegbo, M, Crowe, J.E. | Deposit date: | 2012-10-05 | Release date: | 2013-05-29 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore. Plos One, 8, 2013
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4GSD
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![BU of 4gsd by Molmil](/molmil-images/mine/4gsd) | H5.3 Fab Structure | Descriptor: | H5.3 Fab Heavy Chain, H5.3 Fab Light Chain | Authors: | Spiller, B.W, Winarski, K.L. | Deposit date: | 2012-08-27 | Release date: | 2013-08-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. J.Clin.Invest., 123, 2013
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6V5D
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![BU of 6v5d by Molmil](/molmil-images/mine/6v5d) | EROS3 RDC and NOE Derived Ubiquitin Ensemble | Descriptor: | Ubiquitin | Authors: | Lange, O.F, Lakomek, N.A, Smith, C.A, Griesinger, C, de Groot, B.L. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Enhancing NMR derived ensembles with kinetics on multiple timescales. J.Biomol.Nmr, 74, 2020
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2KN5
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![BU of 2kn5 by Molmil](/molmil-images/mine/2kn5) | |
4OR2
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![BU of 4or2 by Molmil](/molmil-images/mine/4or2) | Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, CHOLESTEROL, ... | Authors: | Wu, H, Wang, C, Gregory, K.J, Han, G.W, Cho, H.P, Xia, Y, Niswender, C.M, Katritch, V, Cherezov, V, Conn, P.J, Stevens, R.C, GPCR Network (GPCR) | Deposit date: | 2014-02-10 | Release date: | 2014-03-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator Science, 344, 2014
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