H5.3 Fab Structure

Summary for 4GSD

DescriptorH5.3 Fab Light Chain, H5.3 Fab Heavy Chain (3 entities in total)
Functional Keywordsantibody, immune response, influenza h5 hemagglutanin, immune system
Biological sourceHomo sapiens
Total number of polymer chains2
Total molecular weight46644.99
Spiller, B.W.,Winarski, K.L. (deposition date: 2012-08-27, release date: 2013-08-21, Last modification date: 2018-01-24)
Primary citation
Thornburg, N.J.,Nannemann, D.P.,Blum, D.L.,Belser, J.A.,Tumpey, T.M.,Deshpande, S.,Fritz, G.A.,Sapparapu, G.,Krause, J.C.,Lee, J.H.,Ward, A.B.,Lee, D.E.,Li, S.,Winarski, K.L.,Spiller, B.W.,Meiler, J.,Crowe, J.E.
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses.
J.Clin.Invest., 123:4405-4409, 2013
PubMed: 23999429 (PDB entries with the same primary citation)
DOI: 10.1172/JCI69377
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.205504.1%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution