7Y78
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![BU of 7y78 by Molmil](/molmil-images/mine/7y78) | Crystal structure of Cry78Aa | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | Authors: | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | Deposit date: | 2022-06-21 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7Y79
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![BU of 7y79 by Molmil](/molmil-images/mine/7y79) | Crystal structure of Cry78Aa | Descriptor: | Toxin | Authors: | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | Deposit date: | 2022-06-21 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7YIM
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![BU of 7yim by Molmil](/molmil-images/mine/7yim) | Cryo-EM structure of human Alpha-fetoprotein | Descriptor: | Alpha-fetoprotein | Authors: | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | Deposit date: | 2022-07-17 | Release date: | 2023-01-18 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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7YGW
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![BU of 7ygw by Molmil](/molmil-images/mine/7ygw) | Crystal structure of the Zn2+-bound EFhd1/Swiprosin-2 | Descriptor: | EF-hand domain-containing protein D1, GLYCEROL, ZINC ION | Authors: | Mun, S.A, Park, J, Kang, J.Y, Park, T, Jin, M, Yang, J, Eom, S.H. | Deposit date: | 2022-07-12 | Release date: | 2023-03-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2. Iucrj, 10, 2023
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7YGY
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![BU of 7ygy by Molmil](/molmil-images/mine/7ygy) | Crystal structure of the Zn2+-bound EFhd2/Swiprosin-1 | Descriptor: | EF-hand domain-containing protein D2, ZINC ION | Authors: | Mun, S.A, Park, J, Kang, J.Y, Park, T, Jin, M, Yang, J, Eom, S.H. | Deposit date: | 2022-07-12 | Release date: | 2023-03-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2. Iucrj, 10, 2023
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6KY4
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![BU of 6ky4 by Molmil](/molmil-images/mine/6ky4) | Crystal structure of Sulfiredoxin from Arabidopsis thaliana | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Sulfiredoxin, ... | Authors: | Liu, M, Wang, J, Li, X, Li, M, Sylvanno, M.J, Zhang, M, Wang, M. | Deposit date: | 2019-09-16 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The crystal structure of sulfiredoxin from Arabidopsis thaliana revealed a more robust antioxidant mechanism in plants. Biochem.Biophys.Res.Commun., 520, 2019
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1MP5
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![BU of 1mp5 by Molmil](/molmil-images/mine/1mp5) | Y177F VARIANT OF S. ENTERICA RmlA | Descriptor: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE | Authors: | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | Deposit date: | 2002-09-11 | Release date: | 2002-10-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering Proc.Natl.Acad.Sci.USA, 99, 2002
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1MP4
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![BU of 1mp4 by Molmil](/molmil-images/mine/1mp4) | W224H VARIANT OF S. ENTERICA RmlA | Descriptor: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, W224H Variant of S. Enterica RmlA Bound to UDP-Glucose | Authors: | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | Deposit date: | 2002-09-11 | Release date: | 2002-10-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering Proc.Natl.Acad.Sci.USA, 99, 2002
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1MHK
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![BU of 1mhk by Molmil](/molmil-images/mine/1mhk) | Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn | Descriptor: | BROMIDE ION, RNA 12-mer BCh12, RNA 14-mer BCh12 | Authors: | Szep, S, Wang, J, Moore, P.B. | Deposit date: | 2002-08-20 | Release date: | 2002-09-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of a 26-nucleotide RNA containing a hook-turn RNA, 9, 2003
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1MP3
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![BU of 1mp3 by Molmil](/molmil-images/mine/1mp3) | L89T VARIANT OF S. ENTERICA RmlA | Descriptor: | GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, THYMIDINE-5'-TRIPHOSPHATE | Authors: | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.T, Nikolov, D.B. | Deposit date: | 2002-09-11 | Release date: | 2002-10-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering Proc.Natl.Acad.Sci.USA, 99, 2002
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1MIY
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![BU of 1miy by Molmil](/molmil-images/mine/1miy) | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | Deposit date: | 2002-08-23 | Release date: | 2002-12-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP Cell(Cambridge,Mass.), 111, 2002
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6DDT
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![BU of 6ddt by Molmil](/molmil-images/mine/6ddt) | mouse beta-mannosidase (MANBA) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gytz, H, Liang, J, Liang, Y, Gorelik, A, Illes, K, Nagar, B. | Deposit date: | 2018-05-10 | Release date: | 2019-01-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of mammalian beta-mannosidase provides insight into beta-mannosidosis and nystagmus. FEBS J., 286, 2019
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8EHK
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![BU of 8ehk by Molmil](/molmil-images/mine/8ehk) | |
8EHM
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![BU of 8ehm by Molmil](/molmil-images/mine/8ehm) | |
8EHL
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![BU of 8ehl by Molmil](/molmil-images/mine/8ehl) | |
8EHJ
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![BU of 8ehj by Molmil](/molmil-images/mine/8ehj) | |
7YGF
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![BU of 7ygf by Molmil](/molmil-images/mine/7ygf) | Crystal structure of YggS from Fusobacterium nucleatum | Descriptor: | Pyridoxal phosphate homeostasis protein, SULFATE ION | Authors: | He, S.R, Chan, Y.Y, Wang, L.L, Bai, X, Bu, T.T, Zhang, J, Xu, Y.B. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from Fusobacterium nucleatum. Molecules, 27, 2022
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5CTY
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![BU of 5cty by Molmil](/molmil-images/mine/5cty) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ... | Authors: | Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. | Deposit date: | 2015-07-24 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
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6DU8
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![BU of 6du8 by Molmil](/molmil-images/mine/6du8) | Human Polycsytin 2-l1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | Authors: | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | Deposit date: | 2018-06-20 | Release date: | 2018-07-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Cryo-EM structure of the polycystin 2-l1 ion channel. Elife, 7, 2018
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8GOU
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![BU of 8gou by Molmil](/molmil-images/mine/8gou) | Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH003 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-25 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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6QLD
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![BU of 6qld by Molmil](/molmil-images/mine/6qld) | Structure of inner kinetochore CCAN-Cenp-A complex | Descriptor: | DNA (125-MER), Histone H2A.1, Histone H2B.1, ... | Authors: | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | Deposit date: | 2019-01-31 | Release date: | 2019-10-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574, 2019
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6QLF
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![BU of 6qlf by Molmil](/molmil-images/mine/6qlf) | Structure of inner kinetochore CCAN complex with mask1 | Descriptor: | Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ... | Authors: | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | Deposit date: | 2019-01-31 | Release date: | 2019-10-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574, 2019
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4OI7
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![BU of 4oi7 by Molmil](/molmil-images/mine/4oi7) | RAGE recognizes nucleic acids and promotes inflammatory responses to DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', ... | Authors: | Jin, T, Jiang, J, Xiao, T. | Deposit date: | 2014-01-19 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.104 Å) | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210, 2013
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4FLH
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![BU of 4flh by Molmil](/molmil-images/mine/4flh) | Crystal structure of human PI3K-gamma in complex with AMG511 | Descriptor: | 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Whittington, D.A, Tang, J, Yakowec, P. | Deposit date: | 2012-06-14 | Release date: | 2012-08-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511. J.Med.Chem., 55, 2012
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4OCZ
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![BU of 4ocz by Molmil](/molmil-images/mine/4ocz) | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea | Descriptor: | 1-[1-(2-methylpropanoyl)piperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | Authors: | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morriseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | Deposit date: | 2014-01-09 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J.Med.Chem., 57, 2014
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