4Z6Q
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![BU of 4z6q by Molmil](/molmil-images/mine/4z6q) | Structure of H200N variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with HPCA at 1.57 Ang resolution | Descriptor: | 2-(3,4-DIHYDROXYPHENYL)ACETIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kovaleva, E.G, Lipscomb, J.D. | Deposit date: | 2015-04-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
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4Z6V
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![BU of 4z6v by Molmil](/molmil-images/mine/4z6v) | Structure of H200Q variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-nitrocatechol at 1.37 Ang resolution | Descriptor: | 4-NITROCATECHOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kovaleva, E.G, Lipscomb, J.D. | Deposit date: | 2015-04-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
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4Z6M
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![BU of 4z6m by Molmil](/molmil-images/mine/4z6m) | Structure of H200Q variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum at 1.35 Ang resolution | Descriptor: | CALCIUM ION, CHLORIDE ION, FE (II) ION, ... | Authors: | Kovaleva, E.G, Lipscomb, J.D. | Deposit date: | 2015-04-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
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4Z6S
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![BU of 4z6s by Molmil](/molmil-images/mine/4z6s) | Structure of H200Q variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-sulfonyl catechol at 1.42 Ang resolution | Descriptor: | 3,4-dihydroxybenzenesulfonic acid, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kovaleva, E.G, Lipscomb, J.D. | Deposit date: | 2015-04-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
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4Z6U
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![BU of 4z6u by Molmil](/molmil-images/mine/4z6u) | Structure of H200E variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-nitrocatechol at 1.48 Ang resolution | Descriptor: | 4-NITROCATECHOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kovaleva, E.G, Lipscomb, J.D. | Deposit date: | 2015-04-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
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4Z6O
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![BU of 4z6o by Molmil](/molmil-images/mine/4z6o) | Structure of H200E variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with HPCA at 1.63 Ang resolution | Descriptor: | 2-(3,4-DIHYDROXYPHENYL)ACETIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kovaleva, E.G, Lipscomb, J.D. | Deposit date: | 2015-04-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
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1Q0C
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![BU of 1q0c by Molmil](/molmil-images/mine/1q0c) | Anerobic Substrate Complex of Homoprotocatechuate 2,3-Dioxygenase from Brevibacterium fuscum. (Complex with 3,4-Dihydroxyphenylacetate) | Descriptor: | 2-(3,4-DIHYDROXYPHENYL)ACETIC ACID, FE (III) ION, homoprotocatechuate 2,3-dioxygenase | Authors: | Vetting, M.W, Wackett, L.P, Que, L, Lipscomb, J.D, Ohlendorf, D.H. | Deposit date: | 2003-07-15 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J.Bacteriol., 186, 2004
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1Q0O
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![BU of 1q0o by Molmil](/molmil-images/mine/1q0o) | CRYSTAL STRUCTURE OF HOMOPROTOCATECHUATE 2,3-DIOXYGENASE FROM BREVIBACTERIUM FUSCUM (FULL LENGTH PROTEIN) | Descriptor: | FE (III) ION, homoprotocatechuate 2,3-dioxygenase | Authors: | Vetting, M.W, Wackett, L.P, Que, L, Lipscomb, J.D, Ohlendorf, D.H. | Deposit date: | 2003-07-16 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J.Bacteriol., 186, 2004
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1F1R
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![BU of 1f1r by Molmil](/molmil-images/mine/1f1r) | CRYSTAL STRUCTURE OF HOMOPROTOCATECHUATE 2,3-DIOXYGENASE FROM ARTHROBACTER GLOBIFORMIS (NATIVE, NON-CRYO) | Descriptor: | HOMOPROTOCATECHUATE 2,3-DIOXYGENASE, MANGANESE (II) ION | Authors: | Vetting, M.W, Lipscomb, J.D, Wackett, L.P, Que Jr, L, Ohlendorf, D.H. | Deposit date: | 2000-05-19 | Release date: | 2003-06-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J.Bacteriol., 186, 2004
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1F1V
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![BU of 1f1v by Molmil](/molmil-images/mine/1f1v) | ANAEROBIC SUBSTRATE COMPLEX OF HOMOPROTOCATECHUATE 2,3-DIOXYGENASE FROM ARTHROBACTER GLOBIFORMIS. (COMPLEX WITH 3,4-DIHYDROXYPHENYLACETATE) | Descriptor: | 2-(3,4-DIHYDROXYPHENYL)ACETIC ACID, HOMOPROTOCATECHUATE 2,3-DIOXYGENASE, MANGANESE (II) ION | Authors: | Vetting, M.W, Lipscomb, J.D, Wackett, L.P, Que Jr, L, Ohlendorf, D.H. | Deposit date: | 2000-05-20 | Release date: | 2003-06-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J.Bacteriol., 186, 2004
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1F1U
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![BU of 1f1u by Molmil](/molmil-images/mine/1f1u) | CRYSTAL STRUCTURE OF HOMOPROTOCATECHUATE 2,3-DIOXYGENASE FROM ARTHROBACTER GLOBIFORMIS (NATIVE, LOW TEMPERATURE) | Descriptor: | HOMOPROTOCATECHUATE 2,3-DIOXYGENASE, MANGANESE (II) ION | Authors: | Vetting, M.W, Lipscomb, J.D, Wackett, L.P, Que Jr, L, Ohlendorf, D.H. | Deposit date: | 2000-05-19 | Release date: | 2003-06-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J.Bacteriol., 186, 2004
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7Q2U
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![BU of 7q2u by Molmil](/molmil-images/mine/7q2u) | The crystal structure of the HINT1 Q62A mutant. | Descriptor: | CACODYLATE ION, HEXAETHYLENE GLYCOL, Histidine triad nucleotide-binding protein 1, ... | Authors: | Dolot, R.M, Strom, A.M, Wagner, C.R. | Deposit date: | 2021-10-26 | Release date: | 2021-11-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides. Biochemistry, 61, 2022
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3V5X
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![BU of 3v5x by Molmil](/molmil-images/mine/3v5x) | Structure of FBXL5 hemerythrin domain, C2 cell | Descriptor: | F-box/LRR-repeat protein 5, MU-OXO-DIIRON | Authors: | Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. | Deposit date: | 2011-12-17 | Release date: | 2012-01-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5). J.Biol.Chem., 287, 2012
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3V5Y
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![BU of 3v5y by Molmil](/molmil-images/mine/3v5y) | Structure of FBXL5 hemerythrin domain, P2(1) cell | Descriptor: | F-box/LRR-repeat protein 5, MU-OXO-DIIRON | Authors: | Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. | Deposit date: | 2011-12-17 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5). J.Biol.Chem., 287, 2012
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5MND
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![BU of 5mnd by Molmil](/molmil-images/mine/5mnd) | |
3V5Z
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![BU of 3v5z by Molmil](/molmil-images/mine/3v5z) | Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically | Descriptor: | F-box/LRR-repeat protein 5, MU-OXO-DIIRON | Authors: | Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. | Deposit date: | 2011-12-17 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1847 Å) | Cite: | Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5). J.Biol.Chem., 287, 2012
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6YD0
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![BU of 6yd0 by Molmil](/molmil-images/mine/6yd0) | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, diferric state | Descriptor: | FE (III) ION, GLYCEROL, Methane monooxygenase, ... | Authors: | Srinivas, V, Hogbom, M. | Deposit date: | 2020-03-19 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States. J. Am. Chem. Soc., 142, 2020
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6YDU
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![BU of 6ydu by Molmil](/molmil-images/mine/6ydu) | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, reoxidized diferric state, 10s O2 exposure. | Descriptor: | FE (III) ION, GLYCEROL, Methane monooxygenase, ... | Authors: | Srinivas, V, Hogbom, M. | Deposit date: | 2020-03-21 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States. J. Am. Chem. Soc., 142, 2020
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6YY3
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![BU of 6yy3 by Molmil](/molmil-images/mine/6yy3) | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, t=0 diferrous state prior to oxygen activation | Descriptor: | FE (II) ION, GLYCEROL, Methane monooxygenase, ... | Authors: | Srinivas, V, Hogbom, M. | Deposit date: | 2020-05-04 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States. J. Am. Chem. Soc., 142, 2020
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6YDI
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![BU of 6ydi by Molmil](/molmil-images/mine/6ydi) | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, diferrous state | Descriptor: | FE (II) ION, GLYCEROL, Methane monooxygenase, ... | Authors: | Srinivas, V, Hogbom, M. | Deposit date: | 2020-03-20 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States. J. Am. Chem. Soc., 142, 2020
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5G5J
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![BU of 5g5j by Molmil](/molmil-images/mine/5g5j) | Crystal structure of human CYP3A4 bound to metformin | Descriptor: | CYTOCHROME P450 3A4, Metformin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sevrioukova, I. | Deposit date: | 2016-05-25 | Release date: | 2017-06-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chem Biol, 24, 2017
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5TRX
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![BU of 5trx by Molmil](/molmil-images/mine/5trx) | Room temperature structure of an extradiol ring-cleaving dioxygenase from B.fuscum determined using serial femtosecond crystallography | Descriptor: | CALCIUM ION, CHLORIDE ION, FE (II) ION, ... | Authors: | Kovaleva, E.G, Oberthuer, D, Tolstikova, A, Mariani, V. | Deposit date: | 2016-10-27 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Double-flow focused liquid injector for efficient serial femtosecond crystallography Sci. Rep., 7, 2017
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5U5Q
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![BU of 5u5q by Molmil](/molmil-images/mine/5u5q) | 12 Subunit RNA Polymerase II at Room Temperature collected using SFX | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A. | Deposit date: | 2016-12-07 | Release date: | 2017-03-29 | Last modified: | 2019-11-27 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Double-flow focused liquid injector for efficient serial femtosecond crystallography. Sci Rep, 7, 2017
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5TE2
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![BU of 5te2 by Molmil](/molmil-images/mine/5te2) | Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a mechanism-based inhibitor | Descriptor: | 1,2-ETHANEDIOL, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Maize, K.M, Eiden, C, Aldrich, C.C, Finzel, B.C. | Deposit date: | 2016-09-20 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation. J. Am. Chem. Soc., 139, 2017
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4E37
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![BU of 4e37 by Molmil](/molmil-images/mine/4e37) | Crystal Structure of P. aeruginosa catalase, KatA tetramer | Descriptor: | Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | VanderWielen, B.D, Wilson, J.J, Kovall, R.A. | Deposit date: | 2012-03-09 | Release date: | 2013-03-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | KatA, the Major Catalase in Pseudomonas aeruginosa, Assists in Protecting Anaerobic Bacteria From Metabolic and Exogenous Nitric Oxide To be Published
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