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6P9I
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crystal structure of human anti staphylococcus aureus antibody STAU-399 Fab
Descriptor: human anti staphylococcus aureus antibody STAU-399 Fab heavy chain, human anti staphylococcus aureus antibody STAU-399 Fab light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-06-10
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
6P9H
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BU of 6p9h by Molmil
Crystal structure of human anti staphylococcus aureus antibody STAU-281 Fab in complex with IsdB NEAT2 domain
Descriptor: Human anti staphylococcus aureus antibody STAU-281 Fab heavy chain, Human anti staphylococcus aureus antibody STAU-281 Fab light chain, Iron-regulated heme-iron binding protein
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-06-10
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
7L7E
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BU of 7l7e by Molmil
Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Spike protein S1, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-12-28
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol, 6, 2021
7L7D
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BU of 7l7d by Molmil
Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibody AZD8895
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-12-28
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol, 6, 2021
7MKM
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BU of 7mkm by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, SARS2-38 Fv light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-04-24
Release date:2021-05-12
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
7MKL
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BU of 7mkl by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-38 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-04-24
Release date:2021-05-12
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
6DLB
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BU of 6dlb by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab CH65:1203d4 chimera
Descriptor: CH65:1203d4 Fab heavy chain, CH65:1203d4 Fab light chain, SULFATE ION
Authors:Dong, J, Finn, J.A, Crowe, J.E.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6DLA
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BU of 6dla by Molmil
Crystal structures of an influenza A hemagglutinin antibody Fab CH65:7969d2
Descriptor: CH65:7969d2 Fab heavy chain, CH65:7969d2 Fab light chain, SULFATE ION
Authors:Dong, J, Crowe, J.E, Finn, J.A.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
6DL8
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BU of 6dl8 by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab variant CH67:1203d4 chimera
Descriptor: CH67:1203d4 FAB light chain, Ch67:1203d4 FAB heavy chain
Authors:Dong, J, Finn, J.A, Crowe, J.E.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.805 Å)
Cite:Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020
5UHY
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BU of 5uhy by Molmil
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Descriptor: ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
Authors:Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
3QHF
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BU of 3qhf by Molmil
Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
Descriptor: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-01-25
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3QHZ
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BU of 3qhz by Molmil
Crystal Structure of human anti-influenza Fab 2D1
Descriptor: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-01-26
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
4DAG
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BU of 4dag by Molmil
Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site
Descriptor: Fusion glycoprotein F0, Neutralizing Antibody DS7 heavy chain, Neutralizing Antibody DS7 light chain, ...
Authors:Jardetzky, T.S, Wen, X.
Deposit date:2012-01-12
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3904 Å)
Cite:Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site.
Nat.Struct.Mol.Biol., 19, 2012
4XNQ
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BU of 4xnq by Molmil
Antibody hemagglutinin Complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 Light chain, H5.3 heavy chain, ...
Authors:Spiller, B.W, Winarski, K.L.
Deposit date:2015-01-15
Release date:2015-07-15
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XRC
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BU of 4xrc by Molmil
Antibody hemagglutinin Complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 Fab heavy chain, H5.3 Fab light chain, ...
Authors:Spiller, B.W, Winarski, K.L.
Deposit date:2015-01-20
Release date:2015-07-15
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YAQ
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BU of 4yaq by Molmil
Crystal structure of a computationally optimized PG9 mutant
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PG9_N100FY Fab heavy chain, ...
Authors:Murrell, S, Julien, J.P, Wilson, I.A.
Deposit date:2015-02-17
Release date:2015-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
7SWW
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BU of 7sww by Molmil
SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants
To Be Published
7SWX
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BU of 7swx by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants
To Be Published
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Descriptor: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
Authors:Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-07-01
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
6B9J
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BU of 6b9j by Molmil
Structure of vaccinia virus D8 protein bound to human Fab vv138
Descriptor: Fab vv138 Heavy chain, Fab vv138 Light chain, GLYCEROL, ...
Authors:Zajonc, D.M.
Deposit date:2017-10-10
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
5U68
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Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus
Descriptor: Chimera protein of Fusion glycoprotein F0 and Envelope glycoprotein, MPE8
Authors:Wen, X, Jardetzky, T.S.
Deposit date:2016-12-07
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.083 Å)
Cite:Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus.
Nat Microbiol, 2, 2017
5USL
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BU of 5usl by Molmil
Structure of vaccinia virus D8 protein bound to human Fab vv304
Descriptor: Fab vv304 Heavy chain, Fab vv304 Light chain, IMV membrane protein
Authors:Zajonc, D.M.
Deposit date:2017-02-13
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
5V2A
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BU of 5v2a by Molmil
Crystal structure of Fab H7.167 in complex with influenza virus hemagglutinin from A/Shanghai/02/2013 (H7N9)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H7.167 antibody, Hemagglutinin, ...
Authors:Zhang, H, Zhu, X, Wilson, I.A.
Deposit date:2017-03-03
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.656 Å)
Cite:H7N9 influenza virus neutralizing antibodies that possess few somatic mutations.
J. Clin. Invest., 126, 2016
5W42
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BU of 5w42 by Molmil
Crystal structure of human monoclonal antibody H3v-47 in complex with influenza virus hemagglutinin from A/Minnesota/11/2010 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab H3v-47 heavy chain, ...
Authors:Zhang, H, Wilson, I.A.
Deposit date:2017-06-08
Release date:2018-07-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.569 Å)
Cite:A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
5USH
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BU of 5ush by Molmil
Structure of vaccinia virus D8 protein bound to human Fab vv66
Descriptor: Fab vv66 heavy chain, Fab vv66 light chain, IMV membrane protein
Authors:Zajonc, D.M.
Deposit date:2017-02-13
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018

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