5V2A

Crystal structure of Fab H7.167 in complex with influenza virus hemagglutinin from A/Shanghai/02/2013 (H7N9)

Replaces:  5F45

Summary for 5V2A

• Entry DOI: 10.2210/pdb5v2a/pdb
• Descriptor: Hemagglutinin, Light chain (kappa) of H7.167 antibody, Heavy chain of H7.167 antibody, ... (6 entities in total)
• Functional Keywords: hemagglutinin, receptor-binding site, human antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus (A/chicken/Henan/109/2013(H7N9)); More
• Total number of polymer chains: 4
• Total formula weight: 104929.01

Authors

Zhang, H.,Zhu, X.,Wilson, I.A. (deposition date: 2017-03-03, release date: 2017-04-05, Last modification date: 2023-10-04)

• Primary citation: Thornburg, N.J.,Zhang, H.,Bangaru, S.,Sapparapu, G.,Kose, N.,Lampley, R.M.,Bombardi, R.G.,Yu, Y.,Graham, S.,Branchizio, A.,Yoder, S.M.,Rock, M.T.,Creech, C.B.,Edwards, K.M.,Lee, D.,Li, S.,Wilson, I.A.,Garcia-Sastre, A.,Albrecht, R.A.,Crowe, J.E.; H7N9 influenza virus neutralizing antibodies that possess few somatic mutations.; J. Clin. Invest., 126:1482-1494, 2016; PubMed: 26950424; DOI: 10.1172/JCI85317

Experimental method

X-RAY DIFFRACTION (4.656 Å)