7MKM
SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement)
Summary for 7MKM
Entry DOI | 10.2210/pdb7mkm/pdb |
EMDB information | 23898 23899 |
Descriptor | Spike protein S1, SARS2-38 Fv heavy chain, SARS2-38 Fv light chain, ... (4 entities in total) |
Functional Keywords | glycoprotein, antibody, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 3 |
Total formula weight | 45379.63 |
Authors | Adams, L.J.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-04-24, release date: 2021-05-12, Last modification date: 2021-12-01) |
Primary citation | VanBlargan, L.A.,Adams, L.J.,Liu, Z.,Chen, R.E.,Gilchuk, P.,Raju, S.,Smith, B.K.,Zhao, H.,Case, J.B.,Winkler, E.S.,Whitener, B.M.,Droit, L.,Aziati, I.D.,Bricker, T.L.,Joshi, A.,Shi, P.Y.,Creanga, A.,Pegu, A.,Handley, S.A.,Wang, D.,Boon, A.C.M.,Crowe Jr., J.E.,Whelan, S.P.J.,Fremont, D.H.,Diamond, M.S. A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope. Immunity, 54:2399-2416.e6, 2021 Cited by PubMed: 34481543DOI: 10.1016/j.immuni.2021.08.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.16 Å) |
Structure validation
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