5USH

Structure of vaccinia virus D8 protein bound to human Fab vv66

Summary for 5USH

Entry DOI	10.2210/pdb5ush/pdb
Related	4ETQ 5USI 5USL
Descriptor	IMV membrane protein, Fab vv66 heavy chain, Fab vv66 light chain, ... (4 entities in total)
Functional Keywords	viral protein, antibody, fab, immune response, ig fold, viral protein-immune system complex, viral protein/immune system
Biological source	Vaccinia virus More
Total number of polymer chains	6
Total formula weight	148736.21
Authors	Zajonc, D.M. (deposition date: 2017-02-13, release date: 2017-09-20, Last modification date: 2023-10-04)
Primary citation	Matho, M.H.,Schlossman, A.,Gilchuk, I.M.,Miller, G.,Mikulski, Z.,Hupfer, M.,Wang, J.,Bitra, A.,Meng, X.,Xiang, Y.,Kaever, T.,Doukov, T.,Ley, K.,Crotty, S.,Peters, B.,Hsieh-Wilson, L.C.,Crowe, J.E.,Zajonc, D.M. Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8. J. Biol. Chem., 293:390-401, 2018 Cited by PubMed: 29123031 DOI: 10.1074/jbc.M117.814541 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation